Results 111 to 120 of about 10,331,359 (299)

Which clinical signs predict hypoxaemia in young Senegalese children with acute lower respiratory tract disease? [PDF]

, 2015
BACKGROUND Acute lower respiratory tract diseases are an important cause of mortality in children in resource-limited settings. In the absence of pulse oximetry, clinicians rely on clinical signs to detect hypoxaemia.
Zangger, E., Wandeler, G., Zangger, E, Pauchard, J Y, Diawara, H., Gehri, M., Wandeler, Gilles, Diawara, H, Pauchard, J.Y., Gehri, M   +9 more
core   +1 more source

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

The characterisation of polymicrobial bacterial communities in the lower respiratory tract of individuals with chronic pulmonary disease [PDF]

Microbial diversity encompasses the whole of the Earth’s biosphere and is incredibly vast. The microbial diversity of three disparate micro-environments using two culture-independent techniques (denaturing gradient gel electrophoresis (DGGE) and 454 ...
Purcell, Paul
core  

Early acquisition and high nasopharyngeal co-colonisation by Streptococcus pneumoniae and three respiratory pathogens amongst Gambian new-borns and infants. [PDF]

, 2011
BACKGROUND: Although Haemophilus influenzae type b (Hib), Staphylococcus aureus and Moraxella catarrhalis are important causes of invasive and mucosal bacterial disease among children, co-carriage with Streptococcus pneumoniae during infancy has not been
Bottomley, Christian, Kwambana Brenda A, Barer, Michael R, Martin Antonio, Brenda A Kwambana, Michael R Barer, Antonio Martin, Christian Bottomley, Kwambana, Brenda A, Adegbola Richard A, Bottomley Christian, Adegbola, Richard A, Antonio, Martin, Barer Michael R, Richard A Adegbola   +14 more
core   +2 more sources

Study of the pattern of lower respiratory tract infection within the first year in renal transplant patients

Egyptian Journal of Chest Disease and Tuberculosis, 2015
Renal transplantation is the most common type of solid organ transplantation, although immunosuppressive therapy is essential for the viability of the graft it leads to increased incidence of infection, especially urinary tract and respiratory tract ...
Nasr Affara, Hany Shaarawy
doaj   +1 more source

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring

Advanced Science, EarlyView.
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen, Weiyi Wang, Yang Wang, Yiqiang Wu, Xiaohong Liu, Wei Zhang, Juanjuan Ou   +6 more
wiley   +1 more source

Estimation of the national disease burden of influenza-associated severe acute respiratory illness in Kenya and Guatemala : a novel methodology [PDF]

, 2013
Background: Knowing the national disease burden of severe influenza in low-income countries can inform policy decisions around influenza treatment and prevention.
Njuguna Henry, Mott, Joshua A., Kim A. Lindblade (265496), Henry Njuguna, Marc-Alain Widdowson, Mwanajuma Ngama (132330), Sonja J Olsen, Kim A Lindblade, Katz Mark A., Sidi Kazungu (382842), Joshua A. Mott (382843), Summers Aimee, McCracken John, Wences Arvelo, Sammy Khagayi, John McCracken, Khagayi Sammy, Kazungu Sidi, Aimee Summers (382838), Fuller James A., Marc-Alain Widdowson (123352), D. James Nokes (68994), Daniel R. Feikin (153640), Njuguna, Henry, Fuller, James A., Ngama, Mwanajuma, Daniel R Feikin, Joshua A Mott, Emukule Gideon, Sonja J. Olsen (226208), McCracken, John, Mark A. Katz (310324), Wences Arvelo (358137), Kazungu, Sidi, Mark A Katz, Nivaldo Linares-Perez, Nivaldo Linares-Perez (382840), Nokes D. James, Katz, Mark A., Mott Joshua A., Arvelo Wences, Sidi Kazungu, Olsen Sonja J., Summers, Aimee, Feikin, Daniel R., Olsen, Sonja J., Mwanajuma Ngama, Henry Njuguna (319757), Lindblade Kim A., James A Fuller, John McCracken (382841), Gideon Emukule, James A. Fuller (382837), Linares-Perez Nivaldo, Nokes, D. James, Arvelo, Wences, Emukule, Gideon, Gideon Emukule (336782), Widdowson Marc-Alain, D James Nokes, Linares-Perez, Nivaldo, Khagayi, Sammy, Ngama Mwanajuma, Aimee Summers, Sammy Khagayi (382839), Widdowson, Marc-Alain, Lindblade, Kim A., Feikin Daniel R.   +67 more
core   +1 more source

A Role for Neutrophils in Viral Respiratory Disease

Frontiers in Immunology, 2017
Neutrophils are immune cells that are well known to be present during many types of lung diseases associated with acute respiratory distress syndrome (ARDS) and may contribute to acute lung injury.
Jeremy V. Camp, Colleen B. Jonsson
doaj   +1 more source

Clesrovimab for the Prevention of Respiratory Syncytial Virus Lower Respiratory Tract Disease in Infants

Journal of Pharmacy Technology
Objective: To assess the clinical utility of clesrovimab-cfor (Enflonsia ® ), a newly Food and Drug Administration (FDA)-approved monoclonal antibody, for the prevention of respiratory syncytial virus (RSV) lower respiratory tract infections in infants.
Bradley Phillips, Christopher Jackson, Jordan Phillips   +2 more
openaire   +3 more sources

Usefulness of chest radiographs in children with acute lower respiratory tract disease

The Journal of Pediatrics, 1987
To determine how frequently and under what circumstances the chest radiograph changes pre-x-ray diagnoses and plans for management of suspected acute lower respiratory tract disease, experienced pediatricians performed a three-phased sequential evaluation (observation, history, physical examination), determined an initial diagnosis and the need for a ...
A J, Alario, P L, McCarthy, R, Markowitz, P, Kornguth, N, Rosenfield, J M, Leventhal   +5 more
openaire   +2 more sources