β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Beyond the binary: disparities in food consumption and alcohol intake among Brazilian sexual minorities. [PDF]
Cruz PGCES +7 more
europepmc +1 more source
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel +6 more
wiley +1 more source
Bone, muscle, and physical function measures in older adults according to levels of social disadvantage: a cross-sectional study. [PDF]
Talevski J +7 more
europepmc +1 more source
Carbon nanomaterial‐reinforced epoxy composites exhibit pronounced piezoresistive behavior, enabling intrinsic damage sensing under cyclic and fatigue loading. This review critically compares carbon nanotube and graphene systems, correlating filler content, percolation threshold, and gauge factor with sensing stability and damage evolution.
J. M. Parente +3 more
wiley +1 more source
Analysis of Factors Affecting Child Nutrition in Nepal Using the Nepal Demographic and Health Survey 2022. [PDF]
Baral S, Nakazawa M.
europepmc +1 more source
Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
Prevalence and Determinants of Vitamin A Supplementation Among Somali Children (6-59 Months): A Cross-Sectional Study Using Insights From the SDHS 2020. [PDF]
Hassan MS +4 more
europepmc +1 more source
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source
The effect of grade retention on secondary school performance: Evidence from a natural experiment. [PDF]
Parra-Cely S +2 more
europepmc +1 more source

