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Pregnancy and childbirth are the main risk factors for pelvic floor dysfunction. The main manifestations of this disorder are lower urinary tract symptoms (LUTS) and urinary incontinence (UI).
Octaviyana Nadia Nitasari Simatupang +1 more
doaj +1 more source
Prenatal Intervention for Lower Urinary Tract Obstruction
Hydronephrosis is one of the most common abnormalities detected on routine prenatal ultrasounds, being noted in up to 1% of fetuses. Rarely, severe hydronephrosis coexists with oligohydramnios, which portends a poor prognosis.
David M. Kitchens, C. D. Anthony Herndon
doaj +1 more source
Assessment of Lower Urinary Tract Symptoms and Sexual Function in Women with Metabolic Syndrome [PDF]
Objective To assess lower urinary tract symptoms and sexual function in premenopausal women with metabolic syndrome (MetS). Materials and Methods A total of 34 premenopausal patients over 18 years of age with MetS and who were admitted to our ...
Gökhan Temeltaş +4 more
core +1 more source
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou +9 more
wiley +1 more source
Association between physical activity levels and lower urinary tract symptoms: a cohort study in 20,732 Brazilian men [PDF]
Objective: This study aimed to evaluate the association between physical activity levels and lower urinary tract symptoms in 20,732 Brazilian men. Methods: This cohort study included 20,732 men of ≥40 years of age, who participated in health screening ...
Rafael Mathias Pitta +4 more
doaj +1 more source
Bacteriophages of the Lower Urinary Tract
The discovery of bacteria in the female urinary bladder has fundamentally changed current dogma regarding the urinary tract and related urinary disorders.
Andrea Garretto +3 more
semanticscholar +1 more source
The relationship between infecting organisms and underlying structural anomalies in children with urinary tract infections [PDF]
Introduction: Urinary tract infections (UTIs) are a common cause of morbidity in childhood with potential for renal scarring and reflux nephropathy which can lead to hypertension and end-stage renal failure.
Said Conti, Valerie +3 more
core
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Lower urinary tract dysfunction is clinically important because it may cause urinary tract infections, mainly due to accumulation of residual urine, and adversely affect renal function.
Matjaž Kopač
doaj +1 more source
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai +7 more
wiley +1 more source

