Results 151 to 160 of about 55,560 (291)

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Lower urinary tract dysfunction in children with benign sacrococcygeal teratoma

, 1994
We evaluated 8 girls and 3 boys with benign sacrococcygeal teratoma for lower urinary tract dysfunction. All children underwent ultrasonography of the urinary tract, voiding cystourethrography and at least 2 standard urodynamic evaluations.
Boemers, T. M., van Gool, J. D., de Jong, T. P., Bax, K. M.   +3 more
core  

Glyco‐Nanogels for Modulating Pseudomonas aeruginosa Biofilm

Macromolecular Rapid Communications, EarlyView.
Nanogels presenting α‐galactose and β‐fucose can significantly alter Pseudomonas aeruginosa biofilm dynamics through their interaction with lectins. Application timing is crucial: pre‐treatment reduces biofilm, while treatment after biofilm initiation increases biomass.
Sophia Rosencrantz, Jo Sing Julia Tang, Karina Koenig, Sany Chea, Ruben R. Rosencrantz   +4 more
wiley   +1 more source

Early diagnosis and intervention in congenital lower urinary tract obstruction: time to revise our approach? [PDF]

Pediatr Nephrol
Mulder J, Kohl S, Fontanella F, Hilger AC, Reutter H, Stein R, Weber EC, Westland R.   +7 more
europepmc   +1 more source

Obstruction-induced alterations within the urinary bladder and their role in the pathophysiology of lower urinary tract symptomatology

, 2014
Benign prostatic hyperplasia (BPH) is considered a frequent cause of bladder outlet obstruction (BOO) and lower urinary tract symptoms. This review addresses the bladder response to BOO and focuses on the alterations and biochemical adaptability of the ...
Mitsogiannis, Iraklis, Komninos, Christos   +1 more
core  

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

Movement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar, Pinky Agarwal, Karen Anderson, Daniel Claassen, Marissa Dean, Andrew Duker, Burton Scott, Benjamin Hoehn, Ann Mongan, Ping Lin, Ellen Cahir‐McFarland, Lori Taylor, Glenn Morrison, Ted Yednock, Sanjay Keswani, Henk‐Andre Kroon   +15 more
wiley   +1 more source

Risks and Benefits of Vesicoamniotic Shunting for Lower Urinary Tract Obstruction (LUTO) After Early, Intermediate and Late Onset of Therapy-A Monocentric Study of 104 Treated Cases. [PDF]

Biomedicines
Riehle N, Kohl T.
europepmc   +1 more source

Quantitative Susceptibility Mapping of Kidney Stones: An Ex Vivo MRI Phantom Study

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To visualize and characterize the five most common kidney stone types based on their magnetic susceptibilities in MRI using QSM. Methods Three water‐based agar phantoms were constructed, containing a total of 53 ex vivo kidney stones of varying types and sizes.
Lion H. Mücke, Frederik B. Laun, Ruben de Figueiredo Cardoso, Guillaume Flé, Jennifer Lorenz, Alexander Fichte, Michael Uder, Nadine Bayerl, Jannis Hanspach   +8 more
wiley   +1 more source

Silodosin improves functional consequences of lower urinary tract obstruction secondary to benign prostate hypertrophy, a proof of concept study in the spontaneously hypertensive rat supplemented with testosterone. [PDF]

BMC Urol, 2020
Assaly R, Faugeroux J, Laurin M, Compagnie S, Alexandre L, Giuliano F, Behr-Roussel D.   +6 more
europepmc   +1 more source