Results 91 to 100 of about 637,546 (355)

Interpretation of Bouguer Anomaly to Determine Fault and Subsurface Structure at Blawan-ijen Geothermal Area [PDF]

, 2016
Gravity survey has been acquired by Gravimeter Lacoste & Romberg G-1035 at Blawan-Ijen geothermal area. It was a focusing study from previous research.
Azhari, A. P. (Anjar), Maryanto, S. (Sukir), Rachmansyah, A. (Arief)   +2 more
core   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Ghana airborne geophysics project in the Volta and Keta Basin : BGS final report [PDF]

, 2009
This report describes the work undertaken by BGS between November 2006 and March 2009 in collaboration with Fugro Airborne Surveys Pty Ltd on an airborne geophysical survey and ground reconnaissance mapping of the Volta River and Keta Basins, Ghana ...
Carney, J.N., Jordan, C.J., McDonnell, P., Thomas, C.W.   +3 more
core  

Geochemistry of reduced inorganic sulfur, reactive iron, and organic carbon in fluvial and marine surface sediment in the Laizhou Bay region, China [PDF]

, 2015
Understanding the geochemical cycling of sulfur in sediments is important because it can have implications for both modern environments (e.g., deterioration of water quality) and interpretation of the ancient past (e.g., sediment C/S ratios can be used ...
Bottrell, S, Mortimer, R, Sheng, Y, Shi, W, Sun, Q   +4 more
core   +2 more sources

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Carbon Dioxide Emissions and Their Driving Forces of Land Use Change Based on Economic Contributive Coefficient (ECC) and Ecological Support Coefficient (ESC) in the Lower Yellow River Region (1995–2018)

Energies, 2020
Land use change is the second largest source of greenhouse gas emissions after fossil combustion, which can hurt ecological environment severely. Intensive study on land use carbon emissions is of great significance to alleviate environmental pressure ...
Tianqi Rong, Pengyan Zhang, Wenlong Jing, Yu Zhang, Yanyan Li, Dan Yang, Jiaxin Yang, Hao Chang, Linna Ge   +8 more
semanticscholar   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Video-Based Mapping of Oyster Bottom in the Upper Piscataqua River, Sturgeon Creek, and Spruce Creek [PDF]

, 2009
Towed, underwater videography was used to map and characterize the extent of oyster bottom in the upper Piscataqua River, Sturgeon Creek, and Spruce Creek.
Grizzle, Raymond E., Ward, Krystin M.
core   +1 more source

China’s rising hydropower demand challenges water sector [PDF]

, 2015
Demand for hydropower is increasing, yet the water footprints (WFs) of reservoirs and hydropower, and their contributions to water scarcity, are poorly understood.
AY Hoekstra, B Lehner, BM Fekete, CJ Vörösmarty, CW King, D Bastviken, H Inhaber, HL Huang, I Herath, J Liu, JLDS Soito, M Mekonnen, N Barros, NK Sharma, P Gerbens-Leenes, PH Gleick, PH Gleick, PH Gleick, RE Grumbine, SGSA Rothausen, T Oki, TH Bakken, TH Bakken, V Fthenakis, W Gerbens-Leenes, X Chang   +25 more
core   +3 more sources

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source