Results 111 to 120 of about 637,546 (355)
Advanced Science, EarlyView.Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu +12 more
wiley +1 more source
A four stage evolution of the White Channel gravel: Implications for stratigraphy and palaeoclimates [PDF]
, 2014 Although the White Channel gravel (WCG) of the Klondike district, Yukon, contains gold placers which have been exploited for over a century, few sedimentological studies have been undertaken.
Chapman, Robert +3 more
core
Advanced Science, EarlyView.We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza +19 more
wiley +1 more source
Ecological IndicatorsImproving the coevolution level of the water resources–economy–society–environment (WESE) composite system is important for guaranteeing resource security, maintaining an ecological balance and realizing sustainable development.
Jiaqi Li +6 more
doaj +1 more source
Survey of anadromous fish spawning areas: completion report, project AFC-8 July 1970 - January 1975 for Potomac River drainage, Upper Chesapeake Bay drainage [PDF]
, 1975 This report summarizes Project AFC-8 ("Survey of Anadromous Fish Spawning Areas") stream investigation and improvement activities for the entire study period of July 1970 to January 1975.
Dintaman, Ray, Gabor, John, O'Dell, Jay
core
Test of airborne fluorometer over land surfaces and geologic materials [PDF]
, 1970 Response of an experimental Fraunhofer line discriminator to a wide range of surficial deposits common in deserts and semideserts was tested in the laboratory and from an H-19 helicopter.
Hemphill, W. R., Stoertz, G. E.
core +2 more sources
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Temporal Interference Stimulation Enhances Neural Regeneration
Advanced Science, EarlyView.Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott +15 more
wiley +1 more source
The Nearctic species of Oetophorus (Hymenoptera: Ichneumonidae, Ctenopelmatinae) [PDF]
, 2011 The Nearctic members of the genus Oetophorus Foerster are revised. There are four species, 0. pleuralis (Cresson), and 0. obscurus, O. clavatus, and O. maculatus, new species.
Barron, John R.
core
Stabilizing Atomically Dispersed Au With Adjacent Pt for Spatially Precise Molecule Recognition
Advanced Science, EarlyView.A strategy to stabilize atomically dispersed Au catalysts by introducing Pt atoms into CeO2 supports is presented. Pt incorporation prevents Au aggregation, enhances Au‐O orbital coupling, and enables precise recognition of multi‐functionalized molecules, improving catalytic performance and the structural stability of Au‐based catalysts in ...
Rui Tang +12 more
wiley +1 more source