Results 31 to 40 of about 157,390 (254)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Children hospitalised with bronchiolitis in the first year of life have a lower quality of life nine months later [PDF]

Acta Paediatrica, 2014
Acute bronchiolitis increases the risk of asthma, and reduced quality of life (QoL) is reported in children with asthma and allergy. However, the impact of asthma risk factors on QoL is unclear. This study investigated whether bronchiolitis and common asthma risk factors in infancy had an influence on later QoL.The parents of 209 infants recruited ...
Leif Bjarte, Rolfsjord, Håvard Ove, Skjerven, Egil, Bakkeheim, Kai-Håkon, Carlsen, Jon Olav Gjengstø, Hunderi, Bente Krane, Kvenshagen, Petter, Mowinckel, Karin C, Lødrup Carlsen   +7 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Education as an important aspect in the care of a patient with Chronic Obstructive Pulmonary Disease (COPD)

Journal of Education, Health and Sport, 2017
Chronic Obstructive Pulmonary Disease is a disease that is characterized by persistent bronchial obstruction (by lowering FEV). This handicap shows progressive tendencies and is basically irreversible. Due to the number of deaths and deaths in the world,
Agata Ulenberg, Grzegorz Ulenberg, Mirosława Felsmann, Marzena Humańska, Danuta Ponczek, Maria Dąbrowska   +5 more
doaj   +3 more sources

Assessment of the Quality of Life in Patients with Multiple Sclerosis

Pielęgniarstwo Neurologiczne i Neurochirurgiczne, 2021
Introduction. Each progressive incurable disease has an impact on the level and quality of life of those affected, on their family, professional and social roles.
Halina Kalandyk, Jolanta Dyndur
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

EFFICACY AND SAFETY OF LIPID-LOWERING DRUGS IN PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASES IN THE ELDERLY

Рациональная фармакотерапия в кардиологии, 2016
Effect of hyperlipidemia on morbidity and mortality in elderly patients is considered. Authors also cover issues of efficacy and safety of lipid-lowering therapy in primary and secondary prevention of cardiovascular diseases in patients ≥80 years of age ...
E. A. Ushkalova, O. N. Tkacheva, N. K. Runikhina, N. A. Chukhareva, A. Yu. Bevz   +4 more
doaj   +1 more source

POSTHERPETIC NEURALGIA – CURRENT FACTS AND THERAPEUTIC POSSIBILITIES [PDF]

Romanian Journal of Medical Practice, 2019
Neuropathic pain in postherpetic neuralgia has an impact on important aspects of the patient’s day to day life, lowering it’s quality. Understanding the complex pathophysiological mechanisms of postherpetic neuralgia and assesing the patient’s pain ...
Ana-Maria Cioti, Ana Maria Alexandra Stănescu, Ioana Veronica Grăjdeanu, Daniela Oana Toader, Camelia Cristina Diaconu   +4 more
doaj   +1 more source

Lower urinary tract symptoms impair the quality of life in maintenance hemodialysis patients [PDF]

Renal Replacement Therapy, 2019
Abstract Background With aging, and as the duration of their dependence on dialysis becomes longer, maintenance hemodialysis patients experience decreased urine volume and lose the need to urinate. It is not known whether lower urinary tract symptoms (LUTS) affect the quality of life (QOL) in maintenance hemodialysis patients.
Tadasuke Ando, Takahisa Kamegawa, Toshitaka Shin, Hiromitsu Mimata   +3 more
openaire   +2 more sources