Results 41 to 50 of about 166,895 (259)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Assessment of the Quality of Life in Patients with Multiple Sclerosis
Introduction. Each progressive incurable disease has an impact on the level and quality of life of those affected, on their family, professional and social roles.
Halina Kalandyk, Jolanta Dyndur
doaj +1 more source
Phantom Pain and Health-Related Quality of Life in Lower Limb Amputees [PDF]
Amputation of a limb may affect quality of life. However, little is known concerning health-related quality of life in amputees. The purposes of this study were to describe health-related quality of life in a population of lower limb amputees and to investigate potential determinants, including phantom pain.
van der Schans, CP +3 more
openaire +3 more sources
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Chronic Obstructive Pulmonary Disease is a disease that is characterized by persistent bronchial obstruction (by lowering FEV). This handicap shows progressive tendencies and is basically irreversible. Due to the number of deaths and deaths in the world,
Agata Ulenberg +5 more
doaj +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Effect of hyperlipidemia on morbidity and mortality in elderly patients is considered. Authors also cover issues of efficacy and safety of lipid-lowering therapy in primary and secondary prevention of cardiovascular diseases in patients ≥80 years of age ...
E. A. Ushkalova +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Febuxostat in patients with hyperuricemia and gout: is the nephroprotective effect real?
Hyperuricemia (HU) and gout are independent risk factors for chronic kidney disease (CKD). Worldwide, the increasing prevalence of CKD leads to a deterioration in the quality and duration of life of patients and an increase in mortality.
M. S. Eliseev, Ya. I. Kuzmina
doaj +1 more source
POSTHERPETIC NEURALGIA – CURRENT FACTS AND THERAPEUTIC POSSIBILITIES [PDF]
Neuropathic pain in postherpetic neuralgia has an impact on important aspects of the patient’s day to day life, lowering it’s quality. Understanding the complex pathophysiological mechanisms of postherpetic neuralgia and assesing the patient’s pain ...
Ana-Maria Cioti +4 more
doaj +1 more source

