Results 31 to 40 of about 265 (135)

A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms

Toxins, 2020
Envenomations are complex medical emergencies that can have a range of symptoms and sequelae. The only specific, scientifically-validated treatment for envenomation is antivenom administration, which is designed to alleviate venom effects.
Dwin Grashof, Christina N. Zdenek, James S. Dobson, Nicholas J. Youngman, Francisco Coimbra, Melisa Benard-Valle, Alejandro Alagon, Bryan G. Fry   +7 more
doaj   +1 more source

Effect of seasonal photoperiod on molting in Loxosceles reclusa and Loxosceles laeta spiders (Araneae: Sicariidae)

Journal of Arachnology, 2017
During the winter of 2014–15 in southern California, attempts were made to accelerate immature brown recluse spiders, Loxosceles reclusa Gertsch & Mulaik, 1940, to maturity for a pest control experiment in early spring. Despite food offerings, spiders stopped molting after October although they were maintained at 25° C and had swollen, well-nourished ...
Vetter, Richard S., Penas, Linda M, Hoddle, Mark S   +2 more
openaire   +3 more sources

Cutaneous-visceral loxoscelism due to spider bite Loxosceles laeta in children: associated factors

Revista de Investigaciones Veterinarias del Perú, 2023
El objetivo del estudio fue determinar los factores asociados al loxoscelismo cutáneo-visceral en niños por mordedura de araña Loxosceles laeta. La investigación fue retrospectiva, observacional y longitudinal. La muestra correspondió a todos los pacientes menores de 20 años de edad atendidos en el Instituto Nacional de Salud del Niño (n=74), que ...
Juárez S., Rosa, Hernández I., Henry, Valderrama P., Aldo   +2 more
openaire   +1 more source

The visual spectral sensitivity of the Chilean recluse spider Loxosceles laeta

Journal of Experimental Biology, 2019
Spiders are a large group of arthropods and nearly omnipresent in warm and temperate climates. They rely on tactile and visual information to hunt and breed, but compared to their mechanical senses, little is known about their visual systems. In this study we analyzed the visual spectral sensitivity of the Chilean recluse spider Loxosceles laeta, a ...
Felipe Tapia, Jesús Olivares, Oliver Schmachtenberg   +2 more
openaire   +2 more sources

Specificity of Loxosceles α clade phospholipase D enzymes for choline-containing lipids: Role of a conserved aromatic cage.

PLoS Computational Biology, 2022
Spider venom GDPD-like phospholipases D (SicTox) have been identified to be one of the major toxins in recluse spider venom. They are divided into two major clades: the α clade and the β clade.
Emmanuel E Moutoussamy, Qaiser Waheed, Greta J Binford, Hanif M Khan, Shane M Moran, Anna R Eitel, Matthew H J Cordes, Nathalie Reuter   +7 more
doaj   +1 more source

Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Loxosceles spiders’ venoms consist of a mixture of proteins, including the sphingomyelinases D (SMases D), which are the main toxic components responsible for local and systemic effects in human envenomation.
Priscila Hess Lopes, Mário T. Murakami, Fernanda C. V. Portaro, Kerly Fernanda Mesquita Pasqualoto, Carmen van den Berg, Denise V. Tambourgi   +5 more
doaj   +1 more source

Loxoscelismo en Chile: estudios epidemiológicos, clínicos y experimentales Loxoscelism in Chile: epidemiological, clinical and experimental studies

Revista do Instituto de Medicina Tropical de São Paulo, 1989
Se presenta un enfoque panorámico de estudios epidemiológicos, clínicos y experimentales referentes a Loxosceles laeta y loxoscelismo efectuados en 1955-1988 en Santiago, Chile. Se estudiaron 216 casos de loxoscelismo.
Hugo Schenone, Tirza Saavedra, Antonio Rojas, Fernando Villarroel   +3 more
doaj   +1 more source

Evaluation of mesenchymal cells and dapsone for the treatment of dermonecrotic wounds caused by Loxosceles laeta venom in rabbits

Ciência Animal Brasileira, 2022
This study aimed to evaluate the efficacy of mesenchymal stem cells (MSC), alone or associated with dapsone (DAP), in treating dermonecrotic wounds caused by Loxosceles laeta venom. Twenty-five male rabbits were distributed into five groups.
Guilherme de Caro Martins, Maira Souza Oliveira Barreto, Ana Flávia Machado Botelho, Conrado Gamba, Clara Guerra Duarte, Benito Soto-Blanco, Adriane Pimenta Costa-Val Bicalho, Geovanni Cassali, Alfredo Miranda de Goes, Carlos Delfin Chávez Olórtegui, Marília Martins Melo   +10 more
doaj  

Distribuição das espécies do gênero Loxosceles Heinecken & Lowe, 1835 (Araneae; Sicariidae) no Estado do Paraná

Revista da Sociedade Brasileira de Medicina Tropical, 2005
O Estado do Paraná registra anualmente uma média de 2.577 acidentes loxoscélicos por ano, logo o conhecimento da distribuição das espécies do gênero Loxosceles é extremamente importante para elaboração de ações de controle e manejo.
Emanuel Marques-da-Silva, Marta Luciane Fischer   +1 more
doaj  

Design and Production of a Recombinant Hybrid Toxin to Raise Protective Antibodies against Loxosceles Spider Venom

Toxins, 2019
Human accidents with spiders of the genus Loxosceles are an important health problem affecting thousands of people worldwide. Patients evolve to severe local injuries and, in many cases, to systemic disturbances as acute renal failure, in which cases ...
Paula A. L. Calabria, Lhiri Hanna A. L. Shimokawa-Falcão, Monica Colombini, Ana M. Moura-da-Silva, Katia C. Barbaro, Eliana L. Faquim-Mauro, Geraldo S. Magalhaes   +6 more
doaj   +1 more source