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Recent Advances in Research on Widow Spider Venoms and Toxins [PDF]

open access: yesToxins, 2015
Widow spiders have received much attention due to the frequently reported human and animal injures caused by them. Elucidation of the molecular composition and action mechanism of the venoms and toxins has vast implications in the treatment of ...
Shuai Yan, Xianchun Wang
doaj   +4 more sources

Spider-Venom Peptides as Therapeutics [PDF]

open access: yesToxins, 2010
Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid ...
Glenn F. King   +6 more
doaj   +6 more sources

VenoMS—A Website for the Low Molecular Mass Compounds in Spider Venoms [PDF]

open access: yesMetabolites, 2020
Spider venoms are highly complex mixtures. Numerous spider venom metabolites are uniquely found in spider venoms and are of interest concerning their potential use in pharmacology, agriculture, and cosmetics.
Yvonne M. Forster   +4 more
doaj   +2 more sources

A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms [PDF]

open access: yesToxins, 2020
Envenomations are complex medical emergencies that can have a range of symptoms and sequelae. The only specific, scientifically-validated treatment for envenomation is antivenom administration, which is designed to alleviate venom effects.
Dwin Grashof   +7 more
doaj   +2 more sources

Biotechnological Trends in Spider and Scorpion Antivenom Development [PDF]

open access: yesToxins, 2016
Spiders and scorpions are notorious for their fearful dispositions and their ability to inject venom into prey and predators, causing symptoms such as necrosis, paralysis, and excruciating pain.
Andreas Hougaard Laustsen   +5 more
doaj   +12 more sources

A Proteomics and Transcriptomics Investigation of the Venom from the Barychelid Spider Trittame loki (Brush-Foot Trapdoor) [PDF]

open access: yesToxins, 2013
Although known for their potent venom and ability to prey upon both invertebrate and vertebrate species, the Barychelidae spider family has been entirely neglected by toxinologists. In striking contrast, the sister family Theraphosidae (commonly known as
Eivind A. B. Undheim   +12 more
doaj   +5 more sources

Quo Vadis Venomics? A Roadmap to Neglected Venomous Invertebrates [PDF]

open access: yesToxins, 2014
Venomics research is being revolutionized by the increased use of sensitive -omics techniques to identify venom toxins and their transcripts in both well studied and neglected venomous taxa.
Bjoern Marcus von Reumont   +2 more
doaj   +3 more sources

Prospects and challenges of recombinant spider venom enzymes: insights from Loxosceles and Phoneutria venom protease expressions [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology
Spiders use chemically complex venoms to overpower prey. Such venoms are primarily composed of neurotoxic disulfide-rich peptides, linear peptides, and enzymes.
Josephine Dresler   +11 more
doaj   +2 more sources

Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications

open access: yesMolecules, 2023
Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature’s skilled predators.
Ruiyin Guo   +5 more
doaj   +1 more source

Venom of the Brazilian spider Sicarius ornatus (Araneae, Sicariidae) contains active sphingomyelinase D: potential for toxicity after envenomation. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2013
BACKGROUND:The spider family Sicariidae includes two genera, Sicarius and Loxosceles. Bites by Sicarius are uncommon in humans and, in Brazil, a single report is known of a 17-year old man bitten by a Sicarius species that developed a necrotic lesion ...
Priscila Hess Lopes   +5 more
doaj   +1 more source

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