Results 1 to 10 of about 2,873 (206)
VenoMS—A Website for the Low Molecular Mass Compounds in Spider Venoms [PDF]
Metabolites, 2020 Spider venoms are highly complex mixtures. Numerous spider venom metabolites are uniquely found in spider venoms and are of interest concerning their potential use in pharmacology, agriculture, and cosmetics.
Yvonne M. Forster +4 more
doaj +10 more sources
Recent Advances in Research on Widow Spider Venoms and Toxins [PDF]
Toxins, 2015 Widow spiders have received much attention due to the frequently reported human and animal injures caused by them. Elucidation of the molecular composition and action mechanism of the venoms and toxins has vast implications in the treatment of ...
Xianchun Wang, Wang Xianchun
exaly +5 more sources
A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms [PDF]
Toxins, 2020 Envenomations are complex medical emergencies that can have a range of symptoms and sequelae. The only specific, scientifically-validated treatment for envenomation is antivenom administration, which is designed to alleviate venom effects.
Dwin Grashof +7 more
doaj +3 more sources
Anticancer, antimicrobial, and analgesic activities of spider venoms [PDF]
Toxicology Research, 2018 Spider venoms are complex mixtures composed of a variety of compounds, including salts, small organic molecules, peptides, and proteins. But, the venom of a few species is dangerous to humans.
Hassan M Akef
exaly +3 more sources
Pharmacology and biochemistry of spider venoms
Toxicon, 2002 Spider venoms represent an incredible source of biologically active substances which selectively target a variety of vital physiological functions in both insects and mammals. Many toxins isolated from spider venoms have been invaluable in helping to determine the role and diversity of neuronal ion channels and the process of exocytosis.
Lachlan D Rash, Wayne C Hodgson
exaly +7 more sources
The biology and evolution of spider venoms [PDF]
Biological Reviews, 2021 ABSTRACTSpiders are diverse, predatory arthropods that have inhabited Earth for around 400 million years. They are well known for their complex venom systems that are used to overpower their prey. Spider venoms contain many proteins and peptides with highly specific and potent activities suitable for biomedical or agrochemical applications, but the key
Tim Lüddecke +3 more
openaire +6 more sources
Spider-Venom Peptides as Therapeutics [PDF]
Toxins, 2010 Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid ...
Glenn F. King +6 more
doaj +6 more sources
Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates [PDF]
Toxins, 2023 Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira +9 more
doaj +2 more sources
Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications
Molecules, 2023 Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature’s skilled predators.
Ruiyin Guo +5 more
doaj +2 more sources
Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics [PDF]
Toxins, 2019 Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make
Daniele Chaves-Moreira +11 more
doaj +2 more sources