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Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications [PDF]
Molecules, 2023 Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature’s skilled predators.
Ruiyin Guo +5 more
doaj +2 more sources
Genomic and transcriptomic analyses support a silk gland origin of spider venom glands [PDF]
BMC Biology, 2023 Background Spiders comprise a hyperdiverse lineage of predators with venom systems, yet the origin of functionally novel spider venom glands remains unclear.
Bingyue Zhu +5 more
doaj +2 more sources
Venomous spiders of Albania -does an increase of temperature influence the toxicity of spider venom? [PDF]
Toxicon X, 2022 Black widow spiders (Latrodectus sp.) are distributed worldwide, and in Albania the L. tredecimguttatus Rossi, 1790 has been the dominant spider. Other medically important spiders in Albania include the brown recluse with symptoms known as loxoscelism, the false black widow and the egg sac spiders; the last two inducing similar symptoms to a wasp sting.
Vrenozi, Blerina.
europepmc +4 more sources
Spider-Venom Peptides as Therapeutics [PDF]
Toxins, 2010 Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid subjugation of prey.
Natalie J Sáez +2 more
exaly +7 more sources
Enlightening the toxinological dark matter of spider venom enzymes [PDF]
npj BiodiversitySpiders produce highly adapted venoms featuring a complex mixture of biomolecules used mainly for hunting and defense. The most prominent components are peptidic neurotoxins, a major focus of research and drug development, whereas venom enzymes have been
Josephine Dresler +3 more
doaj +2 more sources
VenoMS—A Website for the Low Molecular Mass Compounds in Spider Venoms [PDF]
Metabolites, 2020 Spider venoms are highly complex mixtures. Numerous spider venom metabolites are uniquely found in spider venoms and are of interest concerning their potential use in pharmacology, agriculture, and cosmetics.
Yvonne M. Forster +4 more
doaj +5 more sources
Spider-Venom Peptides as Bioinsecticides [PDF]
Toxins, 2012 Over 10,000 arthropod species are currently considered to be pest organisms. They are estimated to contribute to the destruction of ~14% of the world’s annual crop production and transmit many pathogens. Presently, arthropod pests of agricultural and health significance are controlled predominantly through the use of chemical insecticides ...
Volker Herzig +2 more
exaly +7 more sources
Toxins, 2013 Although known for their potent venom and ability to prey upon both invertebrate and vertebrate species, the Barychelidae spider family has been entirely neglected by toxinologists. In striking contrast, the sister family Theraphosidae (commonly known as
Eivind A B Undheim +2 more
exaly +3 more sources
Phlogiellus bundokalbo spider venom: cytotoxic fractions against human lung adenocarcinoma (A549) cells [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: Spider venom is a potential source of pharmacologically important compounds. Previous studies on spider venoms reported the presence of bioactive molecules that possess cell-modulating activities.
Anna Beatriz R. Mayor +3 more
doaj +3 more sources
Toxicon: X, 2020 Spiders use their venom for defence and to capture prey. These venoms contain a cocktail of biologically active compounds that display several different biological activities, such as large molecules and small molecules including peptides, proteins ...
Prapenpuksiri Rungsa +2 more
exaly +3 more sources