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Spider Venoms: Biochemical Aspects [PDF]

open access: yesAmerican Zoologist, 1969
SYNOPSIS. The venoms of spiders are quite complex and contain an array of biologically active components. The majority of studies on the biochemical aspects of these venoms have utilized four species: Phoneutria fera, Lycosa erythrognatha, Atrax robustus , and Latrodectus mactans .
openaire   +2 more sources

Revealing the Venomous Secrets of the Spider’s Web

open access: yesJournal of Proteome Research, 2020
Orb-weaving spiders use a highly strong, sticky and elastic web to catch their prey. These web properties alone would be enough for the entrapment of prey; however, these spiders may be hiding venomous secrets in the web, which current research is revealing. Here, we provide strong proteotranscriptomic evidence for the presence of toxin/neurotoxin-like
Franciele Grego Esteves   +11 more
openaire   +4 more sources

A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5

open access: yesFrontiers in Pharmacology, 2021
Spider venoms include various peptide toxins that modify the ion currents, mainly of excitable insect cells. Consequently, scientific research on spider venoms has revealed a broad range of peptide toxins with different pharmacological properties, even ...
Diana Alvarado   +13 more
doaj   +1 more source

Isolation, N-glycosylations and Function of a Hyaluronidase-Like Enzyme from the Venom of the Spider Cupiennius salei. [PDF]

open access: yes, 2015
STRUCTURE OF CUPIENNIUS SALEI VENOM HYALURONIDASE Hyaluronidases are important venom components acting as spreading factor of toxic compounds. In several studies this spreading effect was tested on vertebrate tissue.
Christian Trachsel   +35 more
core   +1 more source

Recent Advances in Research on Widow Spider Venoms and Toxins

open access: yesToxins, 2015
Widow spiders have received much attention due to the frequently reported human and animal injures caused by them. Elucidation of the molecular composition and action mechanism of the venoms and toxins has vast implications in the treatment of ...
Shuai Yan, Xianchun Wang
doaj   +1 more source

Identification of a precursor processing protease from the spider Cupiennius salei essential for venom neurotoxin maturation.

open access: yes, 2018
Spider venom neurotoxins and cytolytic peptides are expressed as elongated precursor peptides, which are post-translationally processed by proteases to yield the active mature peptides.
Wolfgang Nentwig   +11 more
core   +1 more source

Heterophilic antibodies in sera from individuals without loxoscelism cross-react with phospholipase D from the venom of Loxosceles and Sicarius spiders

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2018
Background Loxoscelism is a severe human envenomation caused by Loxosceles spider venom. To the best of our knowledge, no study has evaluated the presence of antibodies against Loxosceles venom in loxoscelism patients without treatment with antivenom ...
Tomás Arán-Sekul   +8 more
doaj   +1 more source

Analysis of High Molecular Mass Compounds from the Spider Pamphobeteus verdolaga Venom Gland. A Transcriptomic and MS ID Approach

open access: yes, 2021
Nowadays, spider venom research focuses on the neurotoxic activity of small peptides. In this study, we investigated high-molecular-mass compounds that have either enzymatic activity or housekeeping functions present in either the venom gland or venom ...
Sebastian Estrada-Gómez, Leidy Johana Vargas-Muñoz   +2 more
core   +1 more source

Characterisation of protein families in spider digestive fluids and their role in extra-oral digestion

open access: yesBMC Genomics, 2017
Background Spiders are predaceous arthropods that are capable of subduing and consuming relatively large prey items compared to their own body size. For this purpose, spiders have evolved potent venoms to immobilise prey and digestive fluids that break ...
André Walter   +6 more
doaj   +1 more source

Composition and toxicity of venom produced by araneophagous white-tailed spiders (Lamponidae: Lampona sp.)

open access: yesScientific Reports, 2022
Prey-specialised spiders are adapted to capture specific prey items, including dangerous prey. The venoms of specialists are often prey-specific and less complex than those of generalists, but their venom composition has not been studied in detail. Here,
Ondřej Michálek   +5 more
doaj   +1 more source

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