Results 31 to 40 of about 5,869 (218)
Multicomponent venom of the spider Cupiennius salei: a bioanalytical investigation applying different strategies [PDF]
, 2012 The multicomponent venom of the spider Cupiennius salei was separated by three different chromatographic strategies to facilitate subsequent analysis of peptidic venom components by tandem mass spectrometry (MALDI-TOF-MS and ESI-MS), Edman degradation ...
Cunningham, Monica +26 more
core +1 more source
The venom gland transcriptome of Latrodectus tredecimguttatus revealed by deep sequencing and cDNA library analysis. [PDF]
PLoS ONE, 2013 Latrodectus tredecimguttatus, commonly known as black widow spider, is well known for its dangerous bite. Although its venom has been characterized extensively, some fundamental questions about its molecular composition remain unanswered.
Quanze He +5 more
doaj +1 more source
Venom-gland transcriptomics and proteomics of the Tibellus oblongus spider
, 2023 The EST database includes 1733 records, including 1263 nucleotide sequences with ORFs, of these 942 have been identified as toxin-coding. The database of peptide sequences was built on the basis of the transcriptomics results.
JULIA KOROLKOVA (3102327) +7 more
core +1 more source
Proteotranscriptomic Insights into the Venom Composition of the Wolf Spider Lycosa tarantula
Toxins, 2020 Spider venoms represent an original source of novel compounds with therapeutic and agrochemical potential. Whereas most of the research efforts have focused on large mygalomorph spiders, araneomorph spiders are equally promising but require more ...
Dominique Koua +7 more
doaj +1 more source
Toxins, 2023 The wandering spider, Phoneutria depilata, is one of Colombia’s most active nocturnal arthropod predators of vertebrates and invertebrates. Its venom has been a relevant subject of study in the last two decades.
Diego Sierra Ramírez +7 more
doaj +1 more source
Brown Recluse spider bite mediated hemolysis: clinical features, a possible role for complement inhibitor therapy, and reduced RBC surface glycophorin A as a potential biomarker of venom exposure. [PDF]
PLoS ONE, 2013 The venom of Loxosceles reclusa (Brown Recluse spider) can cause a severe, life-threatening hemolysis in humans for which no therapy is currently available in the USA beyond supportive measures.
Eric A Gehrie, Hui Nian, Pampee P Young
doaj +1 more source
Linear Peptides—A Combinatorial Innovation in the Venom of Some Modern Spiders
Frontiers in Molecular Biosciences, 2021 In the venom of spiders, linear peptides (LPs), also called cytolytical or antimicrobial peptides, represent a largely neglected group of mostly membrane active substances that contribute in some spider species considerably to the killing power of spider
Lucia Kuhn-Nentwig +8 more
doaj +1 more source
Angewandte Chemie, EarlyView.All three diastereoisomers of an esterase‐sensitive phosphotriester dCDN prodrug demonstrate improved activity. The (Rp,Rp) diastereoisomer shows the highest activity with an EC50 of 1.7 nM in STING activation and displays the most pronounced antitumor activity via intravenous administration, significantly suppressing tumor proliferation, extending the
Zhiqiang Xie +14 more
wiley +2 more sources