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The biology and evolution of spider venoms [PDF]
Biological Reviews, 2022 S.163-178Spiders are diverse, predatory arthropods that have inhabited Earth for around 400 million years. They are well known for their complex venom systems that are used to overpower their prey.
Björn M. von Reumont +7 more
core +6 more sources
Spider-Venom Peptides as Therapeutics [PDF]
Toxins, 2010 Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid ...
Glenn F. King +6 more
doaj +6 more sources
Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates [PDF]
Toxins, 2023 Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira +9 more
doaj +2 more sources
Pharmacology and biochemistry of spider venoms
Toxicon, 2002 Spider venoms represent an incredible source of biologically active substances which selectively target a variety of vital physiological functions in both insects and mammals.
Hodgson, Wayne C. +3 more
core +6 more sources
Toxins, 2019 Solitary wasps use their stinging venoms for paralyzing insect or spider prey and feeding them to their larvae. We have surveyed bioactive substances in solitary wasp venoms, and found antimicrobial peptides together with some other bioactive peptides ...
Marcia Perez dos Santos Cabrera +3 more
doaj +2 more sources
Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics [PDF]
Toxins, 2019 Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make
Daniele Chaves-Moreira +11 more
doaj +2 more sources
Toxins, 2021 Venoms are complex mixtures of biologically active molecules that impact multiple physiological systems. Manufacture of antivenoms (AVs) therefore requires potency testing using in vivo models to ensure AV efficacy. As part of ongoing research to replace
Erin E. Verity +4 more
doaj +2 more sources
Peptide Toxins in Solitary Wasp Venoms
Toxins, 2016 Solitary wasps paralyze insects or spiders with stinging venom and feed the paralyzed preys to their larva. Accordingly, the venoms should contain a variety of constituents acting on nervous systems.
Katsuhiro Konno +2 more
doaj +2 more sources
Anticancer, antimicrobial, and analgesic activities of spider venoms. [PDF]
Toxicol Res (Camb), 2018 Spider venoms are complex mixtures composed of a variety of compounds, including salts, small organic molecules, peptides, and proteins. But, the venom of a few species is dangerous to humans.
Akef HM.
europepmc +2 more sources
Biotechnological Trends in Spider and Scorpion Antivenom Development [PDF]
Toxins, 2016 Spiders and scorpions are notorious for their fearful dispositions and their ability to inject venom into prey and predators, causing symptoms such as necrosis, paralysis, and excruciating pain.
Andreas Hougaard Laustsen +5 more
doaj +2 more sources