Results 51 to 60 of about 209,568 (261)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Are Loyalty Program Members More Loyal than Nonmembers? [PDF]
, 2011 Since the airline industry introduced the first loyalty program in the early 1980s (Lacey and Sneath, 2006), loyalty programs are common in many hospitality sectors including hotels, restaurants, casinos, and rental cars (Baloglu, 2002).
Knutson, Bonnie +2 more
core
Building the Relationship Quality Model: An Investigation of the Chemical Industry
MIX: Jurnal Ilmiah Manajemen, 2019 The purpose of this study is to develop a relationship quality model and investigate the links among the constructs. This empirical study aims to explore the construct's links between the key constituents of relationship quality model: trust ...
Andreas Samudro +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Relationship Between Key Drivers Customer Experience with Perceived Value and Loyalty of Them (Investigation of Players in the Football Premier League as aClubs Internal Costumer) [PDF]
مطالعات رفتار مصرف کننده., 2020 The purpose of this study was to identify the relationship between key customer experience with loyalty and perceived value of the players in the football clubs of the Premier League.
Mozhgan Khodamoradpoor +2 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Impact of Brand Loyalty on Brand Extension [PDF]
, 2012 The key objective of this study is to explore the effects of different dimensions of brand loyalty towards the original brand on the evaluation of brand extensions.
Ahmed Imran , Hunjra +3 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source