Results 81 to 90 of about 148,538 (312)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Developing Evolutionary–Based Domain–Specific Loyalty Scales

open access: yes, 2010
Loyalty has been researched in many areas, but little attention has been paid to whether loyalty is a unitary construct or differs across domains. We suggest that loyalty will differ across domains in accordance with the challenges our ancestors faced ...
Shattuck, Kraig S.
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

AN ANALYSIS OF THE BRAND LOYALTY BASED CONSUMER TYPOLOGY [PDF]

open access: yes
Even though the number of brands has strongly increased in recent years, only a few managed to endow themselves with significant brand loyalty. Besides the actual proprietary brand assets, such as patents and trademarks, other major elements like brand ...
Moisescu Ovidiu Ioan, Gica Oana Adriana
core   +2 more sources

THE MEDIATOR EFFECT OF TEAM IDENTIFICATION IN RELATIONSHIP BETWEEN ATTITUDINAL LOYALTY AND BEHAVIORAL LOYALTY: A STUDY ON SOCCER FANS IN TURKEY

open access: yesSport şi Societate, 2017
This study examined the relationships between attitudinal loyalty, behavioral loyalty, team identification, and whether team identification served as a mediator between attitudinal loyalty and behavioral loyalty in a sample of soccer fans. In this study,
Caner ÖZGEN, Metin ARGAN
doaj  

DETERMINANTS OF CUSTOMER LOYALTY AND PROPOSING A CUSTOMER LOYALTY MODEL FOR THE BANKING SECTOR OF PAKISTAN [PDF]

open access: yes
It is always costly to attract new customers, so the managers always try to find ways to retain their current customers and concentrate on different factors which enhances the customer loyalty among the customers of the organizations.
Afsar BILAL
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Examining the Nonlinear Effects in Satisfaction-Loyalty-Behavioral Intentions Model [PDF]

open access: yes
Extant research has widely investigated linear functional forms in satisfaction and loyalty models. Though complex nonlinear nature of satisfaction loyalty link is suggested by several researchers, few attempts have been made to empirically examine ...
Jaiswal, A. K., Niraj, Rakesh
core  

Home - About - Disclaimer - Privacy