Results 111 to 120 of about 1,828,400 (307)

Sphingopyxis sp. IM-1 Reduces Intact Microcystin-LR and Attenuates MC-LR-Associated Inflammatory Gene Expression in Hep3B Hepatocytes

Toxins
Excessive cyanobacterial proliferation and toxin production increasingly threaten freshwater ecosystems, drinking water systems, and public health. Among cyanotoxins, microcystin-LR (MC-LR) is one of the most prevalent variants and is recognized for its hepatotoxicity, with evidence showing it can also alter gut microbiota composition. Previous studies,
Lad, Apurva, Bhatia, Mudit, Birbeck, Johnna A., Kuang, Alex, Furr, Elliot, Westrick, Judy, Seo, Youngwoo, Kang, Dae-Wook, Kennedy, David J., Haller, Steven T.   +9 more
openaire   +1 more source

Gap-Tethered Au@AgAu Raman Tags for the Ratiometric Detection of MC-LR

, 2019
Establishing a simple and accurate assay for detecting Microcystin-LR (MC-LR) is of significant important for the environment and human health. Herein, we develop a ratiometric surface-enhanced Raman scattering (SERS) aptasensor based on internal ...
Yuan Zhao (336512), Yuan Zhao, Han Liu (288039), Wei Zhang, Wei Zhang (405), Fangjie Zheng (6192029), Wei Ke (158476), Fangjie Zheng, Han Liu, Wei Ke, Lixia Shi (6704201), Lixia Shi   +11 more
core   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao, Xudong Yu, Ziqian Shang, Mengyao Tan, Xie Huang, Zaizhi Du, Xiaojiao Wang, Xinrui Yang, Ximei Luo, Weidong Wang, Rong Li, Shenglin Luo   +11 more
wiley   +1 more source

Determination of Lr genes in soft winter wheat varieties of ukrainian selection

, 2014
Aims. The aim of our research was to identify Lr-genes in winter wheat Ukrainian varieties using DNA markers. Methods. DNA was isolated from a mixture of five seeds. Presence of Lr genes was studied by polymerase chain reaction (PCR).
Акинина, Г.Е., Попов, В.Н., Дугарь, Ю.Н., Твердохлеб, Е.В., Зайцева, Г.П.   +4 more
core   +1 more source

Resistance mechanisms involved in complex immunity of wheat against rust diseases

Вавиловский журнал генетики и селекции, 2019
The review is devoted to the disclosure of the modern concept of plant immunity as a hierarchical system of plant host protection, controlled by combinations of major and minor resistance genes (loci).
E. S. Skolotneva, E. A. Salina
doaj   +1 more source

Az Arabidopsis thaliana Col-0 modellnövény gyökérmorfológiájában és a gyökér auxin eloszlásában történő változások, microcystin-LR kezelés hatására

, 2021
Vízvirágzás során felszíni vizekben megjelenő cianobaktériumok által termelt microcystin-LR cianotoxin hatásának vizsgálata Arabidopsis thalaiana Col-0 modellnövényen.
Pózer, Erik Tamás
core  

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

Responses of the Proteome and Metabolome in Livers of Zebrafish Exposed Chronically to Environmentally Relevant Concentrations of Microcystin-LR [PDF]

, 2016
In this study, for the first time, changes in expressions of proteins and profiles of metabolites in liver of the small, freshwater fish Danio rerio (zebrafish) were investigated after long-term exposure to environmentally relevant concentrations of ...
Yufei Hu (1544002), Ping Xie (112003), Giesy, John P., Chen, Liang, He, Jun, John P. Giesy (302766), Chen, Jun, Jun Chen (4238), Liang Chen (73736), Jun He (46556), Hu, Yufei, Xie, Ping   +11 more
core   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Rapidly evolving genes and stress adaptation of two desert poplars, Populus euphratica and P. pruinosa [PDF]

, 2013
Understanding which genes have evolved rapidly with the recent tree speciation in arid habitats can provide valuable insights into different adaptation mechanisms. We employed a comparative evolutionary analysis of expressed sequence tags (ESTs) from two
Penghui Xie (420345), Zhang, Jian, Jianquan Liu (200999), Zhang Jian, Meagher Thomas R., Meagher, Thomas R., Lascoux, Martin, Xie, Penghui, Liu, Jianquan, Thomas R Meagher, Xie Penghui, Lascoux Martin, Martin Lascoux, Jian Zhang (1682), Martin Lascoux (201001), Jianquan Liu, Liu Jianquan, Jian Zhang, Lascoux, Martin,, Thomas R. Meagher (420346), Meagher, Thomas Robert, Penghui Xie   +21 more
core   +1 more source