Results 1 to 10 of about 7,812 (164)
Microcystin-LR Induced Immunotoxicity in Mammals [PDF]
Journal of Toxicology, 2016 Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Exposure to microcystins is a global health problem because of its association with various other pathological effects and people all over the world are ...
Yaqoob Lone +2 more
doaj +3 more sources
Haematology of Clarias gariepinus exposed to Microcystin-LR [PDF]
Beni-Suef University Journal of Basic and Applied Sciences, 2017 A static bioassay experiment was conducted by exposing Clarias gariepinus to 200 mg/L and 400m/L of MCLR solutions for 14 days and 28 days to assess the haematological impacts such as estimation of red blood cells, white blood cell and Thrombocytes ...
Isibor, Patrick Omoregie
core +4 more sources
Toxicology Reports, 2022 Harmful algae that inhabit eutrophic lakes produce cyanotoxic microcystins. Therefore, the relationship between chronic exposure to microcystins via drinking water and organ disorders has been investigated.
Yoshihito Koto +8 more
doaj +1 more source
Scientific Reports, 2022 A strong association between exposure to the common harmful algal bloom toxin microcystin and the altered host gut microbiome has been shown. We tested the hypothesis that prior exposure to the cyanotoxin microcystin-LR may alter the host resistome.
Punnag Saha +11 more
doaj +1 more source
Toxins, 2022 The factors related to cyanotoxin occurrence and its social impact, with comprehension and risk perception being the most important issues, are not yet completely understood in the Cuban context. The objectives of this research were to determine the risk
José Carlos Rodríguez Tito +3 more
doaj +1 more source
Determination of microcystin-LR, employing aptasensors [PDF]
Biosensors and Bioelectronics, 2018 Cyanobacteria produce toxins such as microcystin-LR (MC-LR), which are associated with potential hepatotoxicity in humans. The detection of cyanobacteria and their toxins in drinking water and sea food is therefore crucial. To date, methods such as high performance liquid chromatography (HPLC), protein phosphatase inhibition assay (PPIA), and Raman ...
Hasan Badie Bostan +7 more
openaire +2 more sources
Microcystin-LR does not induce alterations to transcriptomic or metabolomic profiles of a model heterotrophic bacterium. [PDF]
PLoS ONE, 2017 Microcystins are secondary metabolites produced by several freshwater, bloom-forming cyanobacterial species. Microcystin-producing cyanobacteria co-occur with a complex community of heterotrophic bacteria.
Robbie M Martin +6 more
doaj +1 more source
Early physiological and biochemical responses of rice seedlings to low concentration of microcystin-LR [PDF]
, 2013 Microcystin-leucine and arginine (microcystin- LR) is a cyanotoxin produced by cyanobacteria like Microcystis aeruginosa, and it’s considered a threat to water quality, agriculture, and human health.
Azevedo, Catarina +4 more
core +1 more source
Proteasome as a Molecular Target of Microcystin-LR [PDF]
Toxins, 2015 Proteasome degrades proteins in eukaryotic cells. As such, the proteasome is crucial in cell cycle and function. This study proved that microcystin-LR (MC-LR), which is a toxic by-product of algal bloom, can target cellular proteasome and selectively inhibit proteasome trypsin-like (TL) activity. MC-LR at 1 nM can inhibit up to 54% of the purified 20S
Zhu Zhu, Li Zhang, Guoqing Shi
openaire +3 more sources
Toxins, 2023 Microcystin can be present in variable concentrations, phases (dissolved and particulate), and structural forms (congeners), all which impact the toxicity and persistence of the algal metabolite.
Emily F. Pierce, Astrid Schnetzer
doaj +1 more source