Results 41 to 50 of about 11,325 (225)
Decomposition of microcystin-LR by Fenton oxidation
Toxicon, 2001 A novel and promising method of microcystin-LR (mcyst-LR) degradation is reported. The decomposition of this cyanobacterial toxin using Fenton reagent has been observed with very low initial concentrations of H2O2 and Fe2+ (Fe3+) in the reaction mixture. Mcyst-LR was isolated from a laboratory culture of Microcystis aeruginosa PCC 7813.
Gajdek, Piotr +3 more
openaire +3 more sources
Photorelease of microcystin-LR from resuspended sediments [PDF]
Harmful Algae, 2017 A series of ten photolysis experiments was conducted with sediments exposed to Microcystis sp. blooms to determine if sunlight is capable of mobilizing the biotoxin microcystin-LR (MC-LR) into the water column. There was a net photorelease of MC-LR in irradiated suspensions in all cases relative to dark controls, ranging from 0.4 to 192μgL-1g-1 into ...
Robert J, Kieber +6 more
openaire +2 more sources
Epitopes prediction for microcystin-LR by molecular docking
Ecotoxicology and Environmental Safety, 2021 Microcystin-LR (MC-LR) is one of the most worldwide harmful cyanobacterial toxins. A lots of antibodies against MC-LR have been generated and characterized. However, the knowledge about the epitopes of MC-LR was still limited. The objective of this study was to analyze the epitopes of MC-LR and demonstrate the binding mode of MC-LR with its antibody ...
Yuan Liu +10 more
openaire +3 more sources
Exploring the direct effects of microcystin-LR on DNA via using cross-technical means
Ecotoxicology and Environmental Safety, 2022 Microcystin-leucine arginine (MC-LR) is the most toxic and abundant microcystin produced by cyanobacteria. Previous studies have demonstrated that MC-LR can lead to DNA damage by increasing intracellular reactive oxygen species content to induce ...
Huixia Zhang +3 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Microcystin-LR (MC-LR) is a potent hepatotoxin that can cause liver inflammation and injury. However, the mode of action of related inflammatory factors is not fully understood.
Yun Wang +8 more
doaj +1 more source
Recreational exposure during algal bloom in carrasco beach, uruguay: A liver failure case report [PDF]
, 2017 In January 2015, a 20-month-old child and her family took part in recreational activities at Carrasco and Malvín beaches (Montevideo, Uruguay). An intense harmful algae bloom (HAB) was developing along the coast at that time.
Andrinolo, Dario +8 more
core +3 more sources
Journal of Toxicology, 2012 Water samples were collected during 3 years (2004–2007) at three sampling sites in the Rio de la Plata estuary. Thirteen biological, physical, and chemical parameters were determined on the water samples.
L. Giannuzzi +5 more
doaj +1 more source
Effects of microcystin-LR in isolated perfused rat kidney
Brazilian Journal of Medical and Biological Research, 1999 Microcystin is a hepatotoxic peptide which inhibits protein phosphatase types 1 and 2A. The objective of the present study was to evaluate the physiopathologic effects of microcystin-LR in isolated perfused rat kidney.
A.C.L. Nobre +4 more
doaj +1 more source
Cloning and expression of first gene for biodegrading microcystins by Sphingopyxis sp. USTB-05 [PDF]
, 2010 Harmful cyanobacterial blooms (HCBs) in natural waters are a growing environmental problem worldwide because microcystins (MCs) produced by cyanobacteria are potent hepatotoxins and tumor promoters. MCs are resistant against physical and chemical factors.
Hai Yan +4 more
core +2 more sources
Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition [PDF]
, 2008 Inhibition of glycogen synthase kinase 3β (GSK3β) as a consequence of its phosphorylation by protein kinase B/Akt (PKB/Akt) has been implicated in cardiac myocyte hypertrophy in response to endothelin-1 or phenylephrine.
Alsafi, Ali +7 more
core +1 more source