Results 41 to 50 of about 114,699 (211)
Exploring the direct effects of microcystin-LR on DNA via using cross-technical means
Ecotoxicology and Environmental Safety, 2022 Microcystin-leucine arginine (MC-LR) is the most toxic and abundant microcystin produced by cyanobacteria. Previous studies have demonstrated that MC-LR can lead to DNA damage by increasing intracellular reactive oxygen species content to induce ...
Huixia Zhang +3 more
doaj +1 more source
Microcystin-LR in Primary Liver Cancers: An Overview
Toxins, 2022 The cyanobacterial blooms produced by eutrophic water bodies have become a serious environmental issue around the world. After cellular lysing or algaecide treatment, microcystins (MCs), which are regarded as the most frequently encountered cyanobacterial toxins in fresh water, are released into water.
Shen Gu, Mingxuemei Jiang, Bo Zhang
openaire +3 more sources
Journal of Toxicology, 2012 Water samples were collected during 3 years (2004–2007) at three sampling sites in the Rio de la Plata estuary. Thirteen biological, physical, and chemical parameters were determined on the water samples.
L. Giannuzzi +5 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Microcystin-LR (MC-LR) is a potent hepatotoxin that can cause liver inflammation and injury. However, the mode of action of related inflammatory factors is not fully understood.
Yun Wang +8 more
doaj +1 more source
The effects of temperature on Bosmina longirostris susceptibility to microcystin-LR acute toxicity.
PLoS ONE, 2019 Harmful algal blooms are an ongoing threat to many aquatic systems throughout the world. In the Chowan River, North Carolina, the frequency of toxin producing Microcystis aeruginosa blooms has increased since 1975 along with an average 0.71°C rise in ...
Madison C Lamb +2 more
doaj +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Strategies for enhancing sensitivity in lateral flow assays
VIEW, EarlyView.Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed +3 more
wiley +1 more source
Early physiological and biochemical responses of rice seedlings to low concentration of microcystin-LR [PDF]
, 2013 Microcystin-leucine and arginine (microcystin- LR) is a cyanotoxin produced by cyanobacteria like Microcystis aeruginosa, and it’s considered a threat to water quality, agriculture, and human health.
Vasconcelos, Vítor +4 more
core +2 more sources
Scientific Reports, 2018 In this work, we fabricated a novel graphene film composite biosensor for microcystin-LR detection as an alternative to time-consuming, expensive, non-portable and often skills-demanding conventional methods of analysis involved in water quality ...
Wei Zhang, Baoping Jia, Hiroaki Furumai
doaj +1 more source
Regulation of Microcystin-LR-Induced DNA Damage by miR-451a in HL7702 Cells
Toxins, 2019 Microcystin-LR is a cyclic heptapeptide hepatotoxin produced by harmful cyanobacteria. A panel of microRNAs containing miR-451a were found to be significantly changed in normal human liver cells HL7702 after exposure to microcystin-LR (MC-LR) in our ...
Lv Chen +9 more
doaj +1 more source