Results 201 to 210 of about 18,165 (260)
Human Absorption, Metabolism, and Excretion (hAME) Mass Balance Studies in Patients With Cancer
ABSTRACT Radiolabeled mass balance human studies are a critical component of clinical pharmacology programs supporting the development of new investigational drugs. These studies provide information about absorption, metabolism, and excretion (AME) of the parent drug and metabolite(s) in the human body and are normally conducted in healthy volunteers ...
Begoña de las Heras +9 more
wiley +1 more source
Canada's terrestrial ecosystems have historically functioned as a net carbon sink but are increasingly impacted by wildfire and timber harvest. Using wall‐to‐wall, physically coherent estimates of all major carbon pools and fluxes from the Canadian Land Surface Scheme Including Biogeochemical Cycles land surface model, we show that rising wildfire ...
Salvatore R. Curasi +9 more
wiley +1 more source
ABSTRACT Aim Quaternary climatic oscillations have profoundly shaped the genetic structure and geographic distributions of alpine biotas. Understanding how cold‐adapted taxa responded to past climatic shifts is essential for unravelling the processes shaping mountain biodiversity, yet cold‐adapted taxa may have followed divergent refugial histories. We
Emanuele Berrilli +2 more
wiley +1 more source
Caring for Truth: Epistemic Leadership and the Moral Ecology of Healthcare Institutions
ABSTRACT Introduction Contemporary healthcare institutions are increasingly organised through technocratic forms of governance in which auditability, standardisation and metric certainty function as primary indicators of quality and accountability in clinical practice.
Maria Antuna‐Casal, Marta Rios
wiley +1 more source
ABSTRACT Aim More than half of patients with pelvic organ prolapse (POP) complain of lower urinary tract symptoms (LUTS), especially voiding difficulty. Surgical approaches such as laparoscopic sacrocolpopexy (LSC) and transvaginal mesh surgery (TVM) often result in improved voiding function in POP cases.
Kenji Kuroda +6 more
wiley +1 more source
ABSTRACT This study examines the effect of multifaceted interventions based on education (1) and recognition (2) of compliance with standard precautions (SPs). A quasi‐experimental research design with a one‐group pre‐test and post‐test was used. The purposive sample included 71 nurses working in different specialty units at a large hospital in Turkey.
Menevse Yildirim +2 more
wiley +1 more source
Multivariate trait profiling and genetic diversity in a global foxtail millet germplasm panel
Four elite foxtail millet groups discovered from 260 accessions: perfect for breeding climate‐resilient, high‐yielding dual‐purpose crops. Abstract Foxtail millet (Setaria italica L.), known for its climate resilience and dual‐purpose utility, is underutilized in breeding programs despite its agricultural potential.
Y. Zhao +7 more
wiley +1 more source
SUMMARY RNA editing is a post‐transcriptional pyrimidine exchange process that alters plastid and mitochondrial transcripts in nearly all land plants. Although confined to organelles, it is directed by nuclear‐encoded PLS‐type pentatricopeptide repeat (PPR) proteins, each typically recognizing a specific RNA target.
Blake D. Fauskee +3 more
wiley +1 more source

