Results 171 to 180 of about 24,350 (247)

Biological roles of LSD1 beyond its demethylase activity

, 2020
Feiying Gu, Yuxin Lin, Zhun Wang, Xiaoxin Wu, Zhenyue Ye, Yuezhen Wang, Huiyin Lan   +6 more
openalex   +2 more sources

Reversible and irreversible LSD1 inhibitors

, 2016
Environmental factors and lifestyle can alter the way our genes are expressed influencing a network of chemical switches within our cells collectively known as the Epigenome. Among the epigenetic mechanisms orchestrating the gene expression, methylation is of foremost importance and probably fair to say, still incompletely decoded.
openaire   +1 more source

LSD1 inhibition sensitizes anti-PD1 blockade immunotherapy by inhibiting the long-range attack of tumor-derived extracellular vesicles. [PDF]

Acta Pharm Sin B
Zhao Y, Zhang D, Meng L, Shan S, Zhang C, Deng Z, Han C, Kong L.   +7 more
europepmc   +1 more source

Inhibition of Lysine-Specific Demethylase-1 (LSD1/KDM1A) Promotes the Adipogenic Differentiation of hESCs Through H3K4 Methylation [PDF]

, 2016

core   +1 more source

Lysine-specific histone demethylase complex restricts Epstein-Barr virus lytic reactivation. [PDF]

Nat Microbiol
Liao Y, Yan J, Kong IY, Li Z, Ding W, Clark S, Maestri D, Yoshida T, Giulino-Roth L, Gewurz BE.   +9 more
europepmc   +1 more source

Drug Repurposing for AML: Structure-Based Virtual Screening and Molecular Simulations of FDA-Approved Compounds with Polypharmacological Potential. [PDF]

Biomedicines
Abdelsayed M, Boulaamane Y.
europepmc   +1 more source

Related data for "High-throughput protein interactome identifies LSD1 as a regulator of SARS-CoV-2 production through lysine demethylation of viral nucleocapsid protein"

Chen, Minghai
openalex   +1 more source

Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells [PDF]

, 2018
Milica Tošić, Anita L. Allen, Dominica Willmann, Christoph Lepper, Johnny Kim, Delphine Duteil, Roland Schüle   +6 more
openalex   +1 more source

Targeting oral cancer epigenome via LSD1

Aging, 2017
openaire   +2 more sources

Discovery of LD-110 as an Effective LSD1 PROTAC Degrader for the Treatment of Esophagus Squamous Cancer. [PDF]

J Med Chem
Zhuo J, Zhai D, Liu L, Yin Y, Zhong C, Chen Q, You X, Chen L, Yu Q, Xiong X, Sun Y, Han X.   +11 more
europepmc   +1 more source