Results 101 to 110 of about 1,035,856 (262)

Initial treatment strategies and outcomes across haemodynamic thresholds and risk stratification in incident systemic sclerosis–associated pulmonary arterial hypertension: a EUSTAR analysis

Arthritis &Rheumatology, Accepted Article.
Objective Real‐world initial treatment strategies in SSc‐PAH remain incompletely described. We aimed to characterise these strategies across haemodynamic thresholds and risk strata and evaluate outcome associations. Methods We analysed treatment‐naïve SSc‐PAH patients in EUSTAR (2000–2021) fulfilling the 2022 haemodynamic definition.
Hilde Jenssen Bjørkekjær, Cosimo Bruni, Kaspar Broch, Cathrine Brunborg, Patricia E Carreira, Paolo Airò, Carmen Pilar Simeón‐Aznar, Marie‐Elise Truchetet, Alessandro Giollo, Alexandra Balbir‐Gurman, Mickael Martin, Christopher P Denton, Armando Gabrielli, Francesco Del Galdo, Madelon C. Vonk, Håvard Fretheim, Helle Bitter, Øyvind Midtvedt, Arne K. Andreassen, Sverre Høie, Yoshiya Tanaka, Gabriela Riemekasten, Ulf Müller‐Ladner, Marco Matucci‐Cerinic, Ivan Castellví, Elise Siegert, Eric Hachulla, Øyvind Molberg, Oliver Distler, Anna‐Maria Hoffmann‐Vold, on behalf of the EUSTAR collaborators   +30 more
wiley   +1 more source

Late fluid flow in a primitive asteroid revealed by Lu–Hf isotopes in Ryugu

Nature
Carbonaceous asteroids are the source of the most primitive meteorites1 and represent leftover planetesimals that formed from ice and dust in the outer Solar System and may have delivered volatiles to the terrestrial planets2-5. Understanding the aqueous activity of asteroids is key to deciphering their thermal, chemical and orbital evolution, with ...
Tsuyoshi Iizuka, Takazo Shibuya, Takehito Hayakawa, Tetsuya Yokoyama, Ikshu Gautam, Makiko K. Haba, Kengo T. M. Ito, Yuki Hibiya, Akira Yamaguchi, Yoshinari Abe, Jérôme Aléon, Conel M. O’D. Alexander, Sachiko Amari, Yuri Amelin, Ken-ichi Bajo, Martin Bizzarro, Audrey Bouvier, Richard W. Carlson, Marc Chaussidon, Byeon-Gak Choi, Nicolas Dauphas, Andrew M. Davis, Tommaso Di Rocco, Wataru Fujiya, Ryota Fukai, Hiroshi Hidaka, Hisashi Homma, Gary R. Huss, Trevor R. Ireland, Akira Ishikawa, Shoichi Itoh, Noriyuki Kawasaki, Noriko T. Kita, Koki Kitajima, Thorsten Kleine, Shintaro Komatani, Alexander N. Krot, Ming-Chang Liu, Yuki Masuda, Kazuko Motomura, Frédéric Moynier, Kazuhide Nagashima, Izumi Nakai, Ann Nguyen, Larry Nittler, Andreas Pack, Changkun Park, Laurette Piani, Liping Qin, Sara Russell, Naoya Sakamoto, Maria Schönbächler, Lauren Tafla, Haolan Tang, Kentaro Terada, Yasuko Terada, Tomohiro Usui, Sohei Wada, Meenakshi Wadhwa, Richard J. Walker, Katsuyuki Yamashita, Qing-Zhu Yin, Shigekazu Yoneda, Hiroharu Yui, Ai-Cheng Zhang, Tomoki Nakamura, Hiroshi Naraoka, Takaaki Noguchi, Ryuji Okazaki, Kanako Sakamoto, Hikaru Yabuta, Masanao Abe, Akiko Miyazaki, Aiko Nakato, Masahiro Nishimura, Tatsuaki Okada, Toru Yada, Kasumi Yogata, Satoru Nakazawa, Takanao Saiki, Satoshi Tanaka, Fuyuto Terui, Yuichi Tsuda, Sei-ichiro Watanabe, Makoto Yoshikawa, Shogo Tachibana, Hisayoshi Yurimoto   +86 more
openaire   +5 more sources

Low‐Field MRI as a Multiparametric Tool for Large Engineered Tissue Characterization

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Advances in 3D bioprinting have enabled the fabrication of large and complex engineered tissues, but their increasing size demands non‐invasive tools for monitoring structure, maturation, and perfusion. Magnetic Resonance Imaging (MRI) offers unique multiparametric capabilities, yet high‐field systems remain costly and inaccessible for most ...
Yilbert Gimenez, Valernst Martial Gilmus, Elliott Cowles, Lucie Essayan, Vincent Semet, Michel Cabrera, Christophe A. Marquette, Simon A. Lambert, Emma Petiot   +8 more
wiley   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Comparative Analysis of Shear Bond Strength in Orthodontic Brackets Between Milled and 3D-Printed Definitive CAD/CAM Restorations

Applied Sciences
Objective: The objective of this study was to evaluate the effect of different surface treatment methods on the shear bond strength (SBS) of metal brackets bonded to two types of CAD/CAM composite restorations: milled and 3D-printed.
Mohammad A. Aldosari, Noha M. Anany, Razan Alaqeely, Jawaher Alsenaidi, Aref Sufyan, Sameh Talaat, Christoph Bourauel, Tarek M. Elshazly, Abdulaziz Alhotan   +8 more
doaj   +1 more source

How National Culture Shapes the Relationship Between Board Gender Diversity and Environmental Performance: Evidence From Developed Economies

Business Strategy and the Environment, EarlyView.
ABSTRACT This study investigates the moderating role of Hofstede's cultural dimensions on the relationship between board gender diversity and corporate environmental performance, including its components (resource use, emissions management, environmental innovations), across publicly listed companies headquartered in 32 developed economies.
Filip Hampl, Dagmar Vágnerová Linnertová   +1 more
wiley   +1 more source

Melting of old refractory mantle during subduction initiation of the western Pacific plate

Communications Earth & Environment
The source characteristics and melting mechanisms for forearc basalts formed during subduction initiation in the western Pacific plate remain unclear.
Hong-Yan Li, Chun Yang, Marguerite Godard, Jeffrey G. Ryan, Yi-Gang Xu   +4 more
doaj   +1 more source

Small scale purification and biophysical characterization of haptoglobin derived from human Cohn fraction IV

Biotechnology Progress, EarlyView.
Abstract Haptoglobin (Hp) is a polymorphic acute phase α‐2 glycoprotein found in plasma that plays a critical role in binding, neutralizing, and removing cell‐free hemoglobin (Hb) from the circulation. Under clinical conditions characterized by high levels of hemolysis, such as in patients with sickle cell disease (SCD), large quantities of cell‐free ...
Shuwei Lu, Mohd Asim Khan, Pedro Cabrales, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +5 more
wiley   +1 more source

Advances in Sustainable Production of Bio‐Derived 5‐Alkoxymethylfurfural and Levulinate Esters: A Comprehensive Review

Carbon Energy, EarlyView.
The present review discusses the advancement in the catalytic synthesis of 5‐alkoxymethylfurfural (AMF) and levulinate esters (LEs) from the aspects of catalytic systems, reaction mechanisms, product isolation, and techno‐economic analysis, supplying valuable insights toward future sustainable and efficient manufacture of AMF and LEs. ABSTRACT The huge
Jun Zhang, Chunxiang Yang, Yuhe Liao, Jiawei Wang, Chengyu Li, Rui Shan, Haoran Yuan   +6 more
wiley   +1 more source

Mild C─F Activation of Azido(per)Fluoroalkanes

Chemistry – A European Journal, EarlyView.
Mild and selective activation of C(sp3)–F bonds in azido(per)fluoroalkanes using thiolates was developed, leading to novel functionalized azides. The reaction is initiated by nucleophilic attack of the sulfur atom to the terminal nitrogen of the azido group, followed by fluoride ion elimination.
Olena Shaitanova, María Martínez Mallo, Sergii Suikov, Blanka Klepetářová, Josef Filgas, Petr Slavíček, Lucie Bednárová, Petr Beier   +7 more
wiley   +1 more source