Results 211 to 220 of about 315,058 (351)

Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li   +8 more
wiley   +1 more source

Investigating the influence of astringent compounds on oral lubrication and the protective role of proline-rich proteins. [PDF]

open access: yesSci Rep
Ammam I   +9 more
europepmc   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

Two‐Phase Nanofluid Flow in a Non‐Newtonian Model Past a Deformable Sheet With Magnetized Environmental Effects: Statistical Modeling and ANOVA Analysis

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This paper presents a comprehensive numerical analysis of magnetohydrodynamic (MHD) Casson nanofluid movement over a permeable, linearly stretching sheet, integrating the contributions of non‐uniform heat generation or absorption and chemical interaction.
Manoj Kumar Sahoo   +3 more
wiley   +1 more source

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