Results 21 to 30 of about 17,786 (260)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Effect of Micro-Dimple Texture on the Lubrication Characteristics of Elliptical Sliding Pairs Between a Flex Spline and a Novel Forced Wave Generator

Lubricants
The novel forced wave generator (NFWG) is a critical component of the harmonic drive (HD) without a flexible bearing. Tribological design is required to increase the load-carrying capacity and reduce the frictional resistance in the elliptical sliding ...
Zixiang Yi, Hongbing Xin
doaj   +1 more source

Transient Thermo Elastohydrodynamic Lubrication of Asymmetric Polymer Planetary Gear with Addendum Modification

Jixie chuandong, 2022
In order to investigate the thermo elastohydrodynamic lubrication characteristics of internal meshing asymmetrical gears with addendum modification， the transient thermo elastohydrodynamic lubrication of asymmetrical polymer gears with addendum ...
Mingyu Zuo, Youqiang Wang, Guangxiao Jian, Yu Hu, Jun Mo, Yuxin Fang   +5 more
doaj  

Characteristic of Sector Tilting Pad Thrust Bearing with Surface Support

Journal of Harbin University of Science and Technology, 2020
In surface center supported thrust bearing as the research object, get the main lubrication parameters of surface supported thrust bearing by finite element analysis.
LI Yonghai, GUO Xiaodong, SUN Xiangzhi, WANG Lei, ZHAO Hongbo, Gong Yuping, WU Dingchao   +6 more
doaj   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source

A Study on the Lubrication Characteristics and Parameter Influence of a High-Speed Train Herringbone Gearbox

Lubricants
To investigate the lubrication characteristics in high-speed train gearboxes, a two-stage herringbone gearbox with an idle gear was analyzed. The lubricant flow and distribution were shown using the moving particle semi-implicit (MPS) method.
Shuai Shao, Kailin Zhang, Yuan Yao, Yi Liu, Jieren Yang, Zhuangzhuang Xin, Kuangzhou He   +6 more
doaj   +1 more source

Influence of Test Temperature and Test Frequency on Fatigue Life of Aluminum Alloy EN AW‐2618A

Advanced Engineering Materials, EarlyView.
The influence of test temperature and test frequency on the fatigue life of EN AW‐2618A is investigated. High‐cycle fatigue tests are performed at different test temperatures and frequencies on the 1000 h/230°C overaged state. Both test parameters reduce fatigue life due to time‐dependent damage mechanisms.
Ying Han, Julian M. Rosalie, Jan Radners, Mauro Madia, Philipp von Hartrott, Birgit Skrotzki   +5 more
wiley   +1 more source

Experimental study on the lubrication characteristics of porous journal bearings with hydrodynamic shape forming at annular surface under sine-wave vibrated conditions (Examination into the shaft whirling behavior at pivot supported condition by measuring the time history waveform on shaft with parameter of vibrated Frequency changes)

Nihon Kikai Gakkai ronbunshu, 2018
This report describes the study on the lubrication characteristics of porous journal bearings as a DC spindle motor's bearing system made with oil impregnated sintered materials having some hydrodynamic shapes. Herring Bone (I & II), Three Lobed
Shigeru OHTSUKA, Masaki YAKABE, Yasutaka HAYAMIZU, Koichi OTSUKA   +3 more
doaj   +1 more source

Lubrication State Recognition Based on Energy Characteristics of Friction Vibration with EEMD and SVM

Shock and Vibration, 2021
In order to identify different lubrication states, lubrication experiments were carried out on a Bruker UMT-3 tester. The experimental results show that the frequency band energy characteristics of friction vibration signals are different under different
Hai-jie Yu, Hai-jun Wei, Jing-ming Li, Da‐ping Zhou, Li‐dui Wei, Hong Liu   +5 more
doaj   +1 more source