Results 141 to 150 of about 1,568,779 (275)

The United States Leads the Globe in Venture Capital Funding for Orthopaedic Surgery

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To characterize venture capital (VC) investments in orthopaedic surgery over the past 25 years to evaluate trends in global innovation. Methods All VC investments related to orthopaedic surgery between January 2000 and December 2024 were retrospectively evaluated using the PitchBook database (PitchBook Platform, PitchBook Data.
Mathangi Sridharan   +7 more
wiley   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini   +19 more
wiley   +1 more source

A rare case of ischemic stroke following occlusion of the artery of Percheron

open access: yesJournal of the Belgian Society of Radiology, 2015
H. Dechamps   +4 more
doaj   +1 more source

The beneficial effects of leave extract of Commiphora leptophloeos on intestinal mucositis induced by 5-fluorouracil in mice. [PDF]

open access: yesActa Cir Bras
Silva ASD   +14 more
europepmc   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

open access: yesArthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller   +16 more
wiley   +1 more source

Foix-Chavany-Marie or opercular syndrome

open access: yesJournal of the Belgian Society of Radiology, 2015
P. Gillardin   +5 more
doaj   +1 more source

Surgical Reconstruction of Ulcers in Chronic Granulomatous Disease. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Dvoracek LA   +4 more
europepmc   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat   +14 more
wiley   +1 more source

Extracellular vesicles related to familial hypercholesterolemia. [PDF]

open access: yesArch Endocrinol Metab
Silvino JPP   +6 more
europepmc   +1 more source

Iliotibial Band Meniscal Augmentation for a Revision Inside‐Out Lateral Meniscus Radial and Horizontal Cleavage Tear Repair

open access: yesArthroscopy Techniques, EarlyView.
Abstract Surgical repair of complex meniscal tears can be quite challenging, especially in the case of a failed meniscus repair. In this setting, meniscal volume may be lost, leading to an increased risk of osteoarthritis development. To prevent this from occurring, care should be taken to revise these complex tears using an inside‐out technique ...
Rylan A. Behnke   +6 more
wiley   +1 more source

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