Results 11 to 20 of about 700,731 (310)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Composição corporal de estudantes adultos com deficiência intelectual e síndrome de Down

Revista Educação Especial, 2020
A deficiência intelectual (DI) é caracterizada por limitações significativas em funcionamento intelectual e em habilidades adaptativas. A síndrome de Down (SD) é uma condição humana geneticamente determinada com características próprias.
Lívia Caroline Nunes do Nascimento, Luna Mares Lopes de Oliveira, Danielle Souza Nogueira, Elane Regina Andrade, Layane Ferreira Feitoza   +4 more
doaj   +1 more source

Review of casing while drilling technology [PDF]

Podzemni Radovi, 2016
Conventional drilling methods have been plagued with huge operational and financial challenges, such as cost of purchasing, inspecting, handling, transporting the drill equipment and most importantly, tripping in-and-out of the drill string whenever the ...
Pavković Bojan, Bizjak Renato, Petrović Bojan   +2 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

La interpretación del «relato» en la doble obra lucana

Estudios Eclesiásticos, 2020
El objetivo del artículo es tomar parte en el actual debate exegético en torno a la doble obra lucana como relato, en el marco más amplio del estudio narrativo de los Evangelios y del libro de los Hechos de los Apóstoles.
Agustín del Agua
doaj  

Terapia fonoaudiológica intensiva e fissura de palato: relato de caso

Revista CEFAC, 2013
A terapia intensiva tem sido relatada na literatura como uma opção de módulo inicial da terapia convencional, pois a medida que o paciente vai percebendo melhoras em sua fala, passa a ter maior envolvimento e comprometimento com a terapia.
Daiane Pontes de Melo, Márcia Suely Souza de Castro Ramalho, Viviane Castro de Araújo Perillo, Lidiane Cristina Barraviera Rodrigues   +3 more
doaj   +1 more source

Criticizing the Lucas Critique: Macroeconometricians' Response to Robert Lucas [PDF]

, 2016
The standard history of macroeconomics considers Lucas (1976) – “the Lucas Critique” – as a pathbreaking innovation for the discipline. According to this view, Lucas’s article dismissed the traditional macroeconometric practice calling for new ways of conceiving the quantitative evaluation of economic policies.
Goutsmedt, Aurélien, Pinzon-Fuchs, Erich, Renault, Matthieu, Sergi, Francesco   +3 more
openaire   +5 more sources

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Normatização do potencial evocado auditivo de tronco encefálico em recém-nascidos

Revista CEFAC, 2013
OBJETIVO: normatizar os achados do equipamento de PEATE da Clínica de Fonoaudiologia da instituição de origem, em recém-nascidos. MÉTODOS: trata-se de um estudo transversal, exploratório não experimental do qual participaram quarenta recém-nascidos, sem ...
Tamier Viviane Souza Costa, Fernanda Soares Aurélio, Virgínia Braz da Silva, Liliane Barbosa Rodrigues   +3 more
doaj   +1 more source