Results 191 to 200 of about 594,288 (306)

Diagnostic networks for IEM in Brazil: report on 10 years of activity of the LSD Brazil Network, helping Brazil and Latin America to identify patients with lysosomal storage diseases. [PDF]

open access: yesJ Community Genet
Trapp FB   +21 more
europepmc   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

SmI2‐Catalyzed Coupling of Alkyl Housane Ketones and Alkenes in an Approach to Norbornanes

open access: yesAngewandte Chemie International Edition, Accepted Article.
Cross‐coupling strategies involving strain‐release have gained significant recent attention for the construction of complex molecular frameworks, particularly in the context of preparing bioisosteres for medicinal chemistry. While the reactivity of cyclopropanes and bicyclo[1.1.0]butanes (BCBs) has been extensively studied, higher homologues are ...
Debayan Roy   +7 more
wiley   +1 more source

Comparison of Methods for the Preparation of Fatty Acid Methyl Esters for the Analysis of Omega‐3 Rich Oils by Gas Chromatography

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Fatty acid analysis is required in a wide range of industries, and conversion to fatty acid methyl esters followed by gas chromatography is by far the most common method of analysis. However, despite widespread use, there is no consensus on which derivatization method should be used or how the methods compare.
Tharani T. Dissanayake   +5 more
wiley   +1 more source

Advanced Biodegradable Materials: The Development of PBS Hybrid Composites Reinforced With Natural Fibers, Lignin, and Sepiolite for Sustainable Applications

open access: yesJournal of Applied Polymer Science, EarlyView.
Development of hybrid biocomposites based on Bio‐PBS with canabrava, ESB, sepiolite, and lignin to reduce cost and improve properties for injection molding applications. The materials were processed via twin‐screw extrusion and characterized for mechanical, thermal, morphological, and rheological performance.
Lucas Nao Horiuchi   +7 more
wiley   +1 more source

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