Results 141 to 150 of about 617,988 (345)
Clinical Pharmacology in Drug Development, EarlyView.Abstract TAK‐071 is a novel muscarinic M1 positive allosteric modulator under investigation for the treatment of cognitive impairment and falls associated with Parkinson disease (PD). This study evaluated population pharmacokinetics of TAK‐071 following single (1‐160 mg) and multiple (3‐15 mg once daily) oral‐dose TAK‐071 in 112 healthy participants ...
Hongxia Jia +8 more
wiley +1 more source
THE DIAGNOSTIC VALUE OF LUMBAR PUNCTURE IN CEREBRAL AND SPINAL HAEMORRHAGES [PDF]
, 1922 William H. Harris
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu +21 more
wiley +1 more source
Anatomical and Clinical Studies on Lumbar Disc Degeneration [PDF]
, 1949 Sten Friberg, Carl Hirsch
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Minimally invasive anterior, lateral, and oblique lumbar interbody fusion: a literature review.
Annals of Translational Medicine, 2018 David S. Xu +5 more
semanticscholar +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya +9 more
wiley +1 more source
Orthopedic Research and Reviews, 2019 Gerrit J Bouma,1 Wimar van den Brink,2 Larry E Miller,3 Jasper FC Wolfs,4 Mark P Arts5 1Department of Neurosurgery, OLVG and Amsterdam University Medical Centers, Amsterdam, The Netherlands; 2Neurochirurgisch Centrum Zwolle, Zwolle, The Netherlands ...
Bouma GJ +4 more
doaj
ESC Heart Failure, Volume 12, Issue 2, Page 1203-1216, April 2025.The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies +23 more
wiley +1 more source
European Journal of Heart Failure, EarlyView.Proposed algorithm to screen for transthyretin cardiac amyloidosis (ATTR‐CA). AL‐CA, immunoglobulin light‐chain cardiac amyloidosis; AMYLI, AMYLoidosis Index; AUC, area under the curve; IWT, increased wall thickness; LVEF, left ventricular ejection fraction; PYP, pyrophosphate.
Giovanni Battista Bonfioli +11 more
wiley +1 more source