Results 81 to 90 of about 916,600 (394)

Clinical Use of S53P4 Bioactive Glass in the Treatment of Bone Defects and Infected Bone: A Systematic Review of the Quality of Clinical Outcomes and A Grade Assessment

Advanced Healthcare Materials, EarlyView.
Bioactive glass (BAG) S53P4 is a synthetic bone substitute. Clinically it has been used in the treatment of benign bone tumor surgery, in spine surgery, in trauma surgery, in frontal sinus surgery, in diabetic foot osteomyelitis surgery, in mastoid surgery, in oral and maxillofacial surgery in more than 4000 patients, with excellent clinical long‐term ...
Lindfors CES, Arts JJC, Lindfors NC
wiley   +1 more source

Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling. [PDF]

, 2010
Topographic neuronal maps arise as a consequence of axon trajectory choice correlated with the localisation of neuronal soma, but the identity of the pathways coordinating these processes is unknown.
Kania, Artur, Kao, Tzu-Jen, Klar, Avihu, Laufer, Ed, Novitch, Bennett G, Okamoto, Hitoshi, Palmesino, Elena, Rousso, David L, Uemura, Osamu   +8 more
core   +4 more sources

Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives

Advanced Materials, EarlyView.
Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin, Liliang Ouyang, Khoon S. Lim, Antonella Motta, Devid Maniglio, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

An Invariant Geometric Feature for Inter-Subject Lumbar Curve Alignment to Detect Spondylolisthesis

IEEE Access
Spondylolisthesis classification commonly relies on the shift distance (SD) feature. This feature measures the displacement between vertebrae but is sensitive to variations in size and rotational alignment of the vertebrae.
Podchara Klinwichit, Watcharaphong Yookwan, Athita Onuean, Paramate Horkaew, Sornsupha Limchareon, Jun-Su Jang, Suwanna Rasmequan, Krisana Chinnasarn   +7 more
doaj   +1 more source

Structural Interface Engineering Unlocks Native‐Like Mechanics in Biomimetic Intervertebral Discs

Advanced Materials Interfaces, EarlyView.
Engineered interlamellar and radial fibrous interfaces enable biomimetic intervertebral disc constructs to replicate native mechanical behavior. Suture‐reinforced laminates enhance cohesion and shear strength, while radial fibers improve compressive resilience and stress redistribution.
Haim S. Mordechai, Javad Tavakoli, Sarit S. Sivan, Mirit Sharabi   +3 more
wiley   +1 more source

A Review on Millimeter‐Thickness Polycrystalline Perovskite for High‐Performance Direct X‐Ray Detection

Advanced Sensor Research, EarlyView.
Millimeter‐thickness polycrystalline metal halide perovskites (MPMHPs) demonstrate outstanding performance in X‐ray detection and hold promise for applications in high‐resolution imaging at low doses. This review provides a summary of research on X‐ray detectors utilizing MPMHP, encompassing various technologies and optimization strategies. Ultimately,
Yanshuang Ba, Zhuangjie Xu, Fuhui Bai, Xiaoyun Liu, Yanan Gong, Weidong Zhu, He Xi, Dazheng Chen, Chunxiang Zhu, Jincheng Zhang, Yue Hao, Chunfu Zhang   +11 more
wiley   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism

Advanced Science, EarlyView.
Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce, Aert F. Scheper, Aung Myat Phyo, Roisin O’ Flaherty, Richard Drake, Aiden Devitt, Martina Marchetti‐Deschmann, Radka Saldova, Abhay Pandit   +8 more
wiley   +1 more source

Prevention of headache after lumbar puncture: questionnaire survey of neurologists and neurosurgeons in United Kingdom [PDF]

, 1998
No abstract ...
Carson, D., Haldane, G.J., Jamieson, D.R.S., Serpell, M.G.   +3 more
core   +2 more sources

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source