Results 11 to 20 of about 64,206 (131)

Biportal endoscopic discectomy for high-grade migrated lumbar disc herniation.

Journal of Neurosurgery : Spine, 2020
OBJECTIVE Although endoscopic procedures for lumbar disc herniation have improved greatly and offer many advantages, the indications are limited mostly to nonmigrated or low-grade migrated disc herniation.
Taewook Kang, S. Park, G. W. Park, S. Lee, Jong Hoon Park, S. Suh   +5 more
semanticscholar   +1 more source

Greater Socioeconomic Disadvantage is Associated with Worse Symptom Severity at Initial Presentation in Patients Seeking Care for Lumbar Disc Herniation.

Spine, 2020
STUDY DESIGN Retrospective, observational study. OBJECTIVE To determine the association of patient socioeconomic disadvantage, insurance type, and other characteristics on presenting symptom severity in patients with isolated lumbar disc herniation ...
D. Bernstein, N. Merchan, Kathleen Fear, P. Rubery, A. Mesfin   +4 more
semanticscholar   +1 more source

The Clinical Diagnostic Value of Lumbar Intervertebral Disc Herniation Based on MRI Images

Journal of Healthcare Engineering, 2021
MRI was used to measure the changes in the angle of the facet joints of the lumbar spine and analyze the relationship between it and the herniated lumbar intervertebral disc.
Kangxing Zheng, Zihuan Wen, Dehuai Li
semanticscholar   +1 more source

The inflammatory response in the regression of lumbar disc herniation

Arthritis Research & Therapy, 2018
Lumbar disc herniation (LDH) is highly associated with inflammation in the context of low back pain. Currently, inflammation is associated with adverse symptoms related to the stimulation of nerve fibers that may lead to pain.
Carla Cunha, A. J. Silva, P. Pereira, R. Vaz, R. Gonçalves, M. Barbosa   +5 more
semanticscholar   +1 more source

Complications, reoperations, readmissions, and length of hospital stay in 34 639 surgical cases of lumbar disc herniation

The Bone & Joint Journal, 2019
Aims The aims of this study were to determine the rates of surgical complications, reoperations, and readmissions following herniated lumbar disc surgery, and to investigate the impact of sociodemographic factors and comorbidity on the rate of such ...
O. Fjeld, O. Fjeld, L. Grøvle, J. Helgeland, M. Småstuen, M. Småstuen, T. Solberg, J. Zwart, J. Zwart, M. Grotle, M. Grotle   +10 more
semanticscholar   +1 more source

Differences in the Incidence of Symptomatic Cervical and Lumbar Disc Herniation According to Age, Sex and National Health Insurance Eligibility: A Pilot Study on the Disease’s Association with Work

International Journal of Environmental Research and Public Health, 2018
The aim of this research was to identify the differences in the incidence of symptomatic cervical and lumbar disc herniation according to age, sex, and national health insurance eligibility.
Youngki Kim, Dongmug Kang, Il-ho Lee, Se-Yeong Kim   +3 more
semanticscholar   +1 more source

A Comparison of Percutaneous Endoscopic Lumbar Discectomy and Open Lumbar Microdiscectomy for Lumbar Disc Herniation in the Korean: A Meta-Analysis

BioMed Research International, 2018
Background Among the surgical methods for lumbar disc herniation, open lumbar microdiscectomy is considered the gold standard. Recently, percutaneous endoscopic lumbar discectomy is also commonly performed for lumbar disc herniation for its various ...
Manyoung Kim, Sol Lee, H. Kim, Sangyoon Park, Sang-Yeup Shim, D. Lim   +5 more
semanticscholar   +1 more source

PACS‐2 Mitigates NPSC Apoptosis and Intervertebral Disc Degeneration by Preserving MAM Integrity via the SP1/LRRK2/Mfn2 Axis

Advanced Science, EarlyView.
This study investigates the role of PACS‐2 in IDD, demonstrating that it suppresses the nuclear translocation of SP1, thereby downregulating its downstream target LRRK2. This reduces LRRK2‐mediated ubiquitination and degradation of Mfn2 through the JNK pathway, preserving MAM integrity and promoting NPSC survival.
Liang Kang, Jiaqi Wang, Chenhao Zhao, Qiuwei Li, Zhigang Zhang, Huaqing Zhang, Chongyu Jia, Luping Zhou, Yanxin Wang, Yu Chen, Kaixuan Li, Xu Yan, Jie Fang, Haibao Wang, Dandan Wang, Pingping Su, Jingyu Zhang, Zhiwei Chen, Renjie Zhang, Cailiang Shen   +19 more
wiley   +1 more source

Anti‐Swelling Hydrogel Combined With Nucleus Pulposus Cell Exosomes and Senolytic Drugs Efficiently Repair Intervertebral Disc Degeneration

Advanced Science, EarlyView.
In this study, a bifunctional anti‐swelling hydrogel system is developed, which encapsulated anti‐senescence drugs quercetin, dasatinib, nucleus pulposus‐derived exosomes (NP‐Exo) to clear senescent nucleus pulposus cells, regulate the inflammatory disc microenvironment, and enhance nucleus pulposus cells activity, ultimately promoting the repair of ...
Songfeng Chen, Hao Han, Yuhao Zhang, Longyu Li, Zhishuo Wang, Jiaming Zhang, Liang Han, Hongwei Kou, Guowei Shang, Chunfeng Shang, Zikuan Leng, Keya Mao, Chengwei Li, Lin Jin, Hongjian Liu   +14 more
wiley   +1 more source

Comparison of treatments for lumbar disc herniation

Medicine, 2019
Study design: Systematic review with network meta-analysis. Objective: To compare patient outcomes of lumbar discectomy with bone-anchored annular closure (LD + AC), lumbar discectomy (LD), and continuing conservative care (CC) for treatment of lumbar ...
M. Arts, A. Kuršumović, L. Miller, J. Wolfs, J. Perrin, E. Van de Kelft, V. Heidecke   +6 more
semanticscholar   +1 more source