Massive Pulmonary Embolism after Lumbar Spinal Fusion Surgery
Pulmonary embolism (PE) is a rare complication that may result in death after lumbar spinal fusion surgery. Although pulmonary embolism mortality rates decreased with early diagnosis and treatment, delays in the diagnosis of pulmonary embolism is ...
Tülin Akarsu Ayazoğlu +4 more
core +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Evaluation of Outcomes of Posterior lumbar Interbody Fusion for Management of Segmental Degenerative Lumbar Canal Stenosis [PDF]
Background: Lumbar degenerative disorders, such as lumbar spinal stenosis, lumbar disc herniation & lumbar degenerative instability, are prevalent crippling illnesses that occur in the elderly population.Objectives: To analyze the safety and efficacy
Mostafa Elsayed +2 more
doaj +2 more sources
Risk Factors and Surgical Treatment for Recurrent Lumbar Disc Prolapse: A Review of the Literature [PDF]
We aim to present the current evidence on various risk factors and surgical treatment modalities for recurrent lumbar disc herniation (rLDH). Using PubMed, a literature search was performed using the Mesh terms “recurrent disc prolapse,” “herniated ...
Bharat R. Dave +3 more
doaj +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Predictors of prolonged opioid use following lumbar fusion [PDF]
The United States has the highest rate of lumbar fusion in the world.1 The lumbar fusion rate increased 2.4 times between 1998 and 2008.2 Rates of opioid pain reliever (OPR) use at 24 months post-lumbar fusion have been reported in up to 30% to 67% of ...
Connolly, Joseph
core +2 more sources
Background This study primarily aims to examine the effect of lumbar fusion on changes in sagittal pelvic tilt (SPT) in total hip arthroplasty (THA) patients. Methods We reviewed 19 hip osteoarthritic patients undergoing THA with or without lumbar fusion.
Gangyong Huang +5 more
doaj +1 more source
Study Design: Retrospective cohort. Objective: Reoperation to lumbar spinal fusion creates significant burden on patient quality of life and healthcare costs. We assessed rates, etiologies, and risk factors for reoperation following elective 1 to 2 level
Daniel Cummins BS +6 more
doaj +1 more source
Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph +5 more
wiley +1 more source
Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez +5 more
wiley +1 more source

