British Journal of Clinical Pharmacology, EarlyView.Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić +7 more
wiley +1 more source
Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a large retrospective cohort of patients after solid organ transplantation [PDF]
, 2017 Background Cryptococcosis is the third most common invasive fungal infection in solid organ transplant (SOT) recipients. There are no nationally representative data describing the incidence, risk factors, and outcomes of cryptococcosis ...
George, Ige A +3 more
core +2 more sources
Exploring AACA Members' Perceptions of Integrating Technologies in Anatomy Education
Clinical Anatomy, EarlyView.ABSTRACT Advances in educational technologies have transformed the landscape of anatomy instruction, prompting a need to understand faculty perceptions regarding their integration. This study explored the perceptions of members of the American Association of Clinical Anatomists (AACA) views on the use, benefits, and challenges of educational ...
A. Raoof +4 more
wiley +1 more source
Mount Fuji Sign: A Rare Complication of Meningitis
Haseki Tıp Bülteni, 2018 Acute bacterial meningitis is a critical condition also because of associated complications and sequelae besides being a life-threatening infection. The complications may develop due to disease itself, diagnostic procedures or treatment. Pneumocephaly is
Gönül Şengöz +2 more
doaj +1 more source
Failure of lumbar puncture in a patient with spinal epidural lipomatosis: a case report
JA Clinical Reports, 2016 We report a case of difficult lumbar puncture due to the inability to obtain adequate cerebrospinal fluid (CSF) in a patient later diagnosed with spinal epidural lipomatosis (SEL).
Daiki Yamanaka +8 more
doaj +1 more source
Combined Chondroitinase and KLF7 Expression Reduce Net Retraction of Sensory and CST Axons from Sites of Spinal Injury [PDF]
, 2017 Axon regeneration in the central nervous system is limited both by inhibitory extracellular cues and by an intrinsically low capacity for axon growth in some CNS populations.
Blackmore, Murray G. +4 more
core +1 more source
Systematic review of new medics’ clinical task experience by country [PDF]
, 2014 OBJECTIVES: There is a need for research which informs on the overall size and significance of clinical skills deficits among new medics, globally. There is also the need for a meta-review of the similarities and differences between countries in the ...
Dickson GD +4 more
core +1 more source
Cerebral Venous Thrombosis in a Patient with Clinically Isolated Spinal Cord Syndrome
Case Reports in Neurological Medicine, 2013 Background. The association between cerebral venous thrombosis (CVT) and multiple sclerosis (MS) has already been reported in patients with clinically definite MS in relation to intravenous methylprednisolone (IVMP) or previously performed lumbar ...
Jasem Yousef Al-Hashel +3 more
doaj +1 more source
Posterior reversible encephalopathy syndrome (PRES) after bevacizumab therapy for metastatic colorectal cancer. [PDF]
, 2018 Posterior reversible encephalopathy syndrome (PRES) is an increasingly recognizable neuro-clinical syndrome. Clinical and neurological manifestations of PRES include hypertension, headache, encephalopathy, seizures, and symmetrical white matter changes ...
Ghani, Ali +5 more
core +2 more sources