Results 181 to 190 of about 228,011 (281)

miR‐214‐3p and NCKAP1: A microglial functional dimension of Alzheimer's progression

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Biological Alzheimer's disease (AD) pathology does not fully explain the marked heterogeneity in clinical severity or progression. We investigated whether patient‐derived induced microglia‐like cell (iMG) profiles capture a functional dimension of AD progression beyond conventional plasma biomarkers.
Min‐Young Noh   +17 more
wiley   +1 more source

Virtual reality training on lumbar puncture quality (VIRTUAL): a randomized controlled trial. [PDF]

open access: yesBMC Med Educ
Zou X   +20 more
europepmc   +1 more source

LUMBAR-PUNCTURE HEADACHE [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1950
openaire   +2 more sources

Network‐dependent remote effects and local tau burden jointly shape neuronal dysfunction in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract BACKGROUND Tau pathology in Alzheimer's disease (AD) propagates along the brain's connectome, yet the mechanisms by which tau drives neuronal dysfunction remain unclear. We hypothesized that dysfunction primarily emerges in regions close to tau‐harboring epicenters. METHODS One hundred thirty‐one amyloid‐positive individuals underwent dynamic [
Lukas Frontzkowski   +28 more
wiley   +1 more source

Cross‐cohort NULISAseq identifies tau‐anchored CSF and plasma‐specific signatures across the amyloid‐positive Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION ATN‐stratified cerebrospinal fluid (CSF) proteomic signals may partly reflect classifier tau immunoassays; reproducible non‐tau signals and CSF–plasma differences remain unclear. METHODS We profiled CSF from 60 A+ Beijing patients with Alzheimer's disease (AD) and 875 A+ Alzheimer's Disease Neuroimaging Initiative (ADNI ...
Lan Ding   +11 more
wiley   +1 more source

Multi‐Center Evaluation of Opioid Administration or Prescription in Pediatric Oncology Patients Using the OMOP CDM

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Purpose Opioid use in pediatric oncology is poorly characterized. The primary objective was to describe opioid administration or prescription patterns in pediatric oncology patients. Methods In this multi‐center retrospective study conducted across three sites, we included patients aged 0–19 years with a malignant neoplastic disease who ...
Yuqing Feng   +17 more
wiley   +1 more source

Severe Pediatric MOGAD‐Associated ADEM With Persistent Neurological Morbidity and Later‐Onset Epilepsy of Uncertain Etiology: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This report describes a 7‐year‐old boy with MOGAD presenting as severe ADEM with fever, encephalopathy, seizures, markedly elevated intracranial pressure, diffuse multifocal MRI abnormalities, and serum MOG‐IgG positivity. He required intravenous corticosteroids, plasma exchange, IVIG, and tocilizumab, followed by rehabilitation and ...
Desiree‐Anne Ramsaran   +2 more
wiley   +1 more source

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