'UltraGUD LP'-ultrasound guided diagnostic LP-a randomizedcontrolled trial. Traditional landmark based lumbar puncture is as effective as ultrasound guided lumbar puncture in outpatient neurology settings. [PDF]
Renga V +3 more
europepmc +1 more source
Abstract The Biofluid Biomarkers Best Practices Workgroup of the National Alzheimer's Coordinating Center–Alzheimer's Disease Research Center (ADRC) Biomarker Core Steering Committee was convened to update pre‐analytical handling guidelines for biofluid biomarkers, focusing on cerebrospinal fluid (CSF) and blood.
Timothy E. Van Meter +21 more
wiley +1 more source
Normal opening pressure lumbar puncture in cryptococcal meningitis complicated by a cerebral venous thrombosis: a case report and literature review. [PDF]
Tee V +4 more
europepmc +1 more source
Abstract INTRODUCTION Recruitment and retention remains a major challenge in Alzheimer's disease research. This study examined the impact of describing potential financial compensation during recruitment on participant enrollment to a longitudinal cohort. METHODS Participant recruitment calls (N = 337) were randomized to either a compensation‐mentioned
Matthew Gabel +6 more
wiley +1 more source
Watching the eye with Mars in sight
Experimental Physiology, EarlyView.
Peter zu Eulenburg +2 more
wiley +1 more source
Integrating polygenic and transcriptional risk scores for detecting Alzheimer's disease
Abstract INTRODUCTION Early detection of Alzheimer's disease (AD) is essential, yet existing biomarkers are invasive or costly. Polygenic risk scores (PRS) and transcriptional risk scores (TRS) may offer accessible alternatives, but their combined predictive performance remains understudied.
Jiyun Hwang +10 more
wiley +1 more source
Usage and positivity rates of Alzheimer's disease biomarkers in a memory clinic
Abstract INTRODUCTION Usage of biomarker tests for Alzheimer's disease pathology and rates of positivity were assessed at the Washington University Memory Diagnostic Center. METHODS Patients who underwent at least one biomarker test for clinical purposes between June 2021 and March 2025 were included (n = 1136). Data were retrospectively extracted from
Anna Hofmann +20 more
wiley +1 more source
Transient penile erection following lumbar puncture with intrathecal prophylaxis in primary testicular diffuse large B-cell lymphoma: a case report. [PDF]
Wang T, Yang J, Ma H.
europepmc +1 more source
Effects of α‐synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging
Abstract INTRODUCTION α‐Synuclein is the hallmark pathology of Parkinson's disease and dementia with Lewy bodies, described together as Lewy body disease (LBD). We investigated effects of α‐syn biomarker positivity in clinically unimpaired (CU) individuals.
Joseph R. Winer +22 more
wiley +1 more source

