Results 31 to 40 of about 104,993 (291)

ING116070: a study of the pharmacokinetics and antiviral activity of dolutegravir in cerebrospinal fluid in HIV-1-infected, antiretroviral therapy-naive subjects. [PDF]

, 2014
BackgroundDolutegravir (DTG), a once-daily, human immunodeficiency virus type 1 (HIV-1) integrase inhibitor, was evaluated for distribution and antiviral activity in cerebrospinal fluid (CSF).MethodsING116070 is an ongoing, single-arm, open-label ...
Chen, Shuguang, extended ING116070 study team, Letendre, Scott L, Mills, Anthony M, Min, Sherene S, Piscitelli, Stephen C, Song, Ivy H, Tashima, Karen T, Thomas, Deborah A   +8 more
core   +3 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Nosocomial meningitis diagnostic test characteristics: a systematic review

Infection Prevention in Practice
Summary: Background: The incidence of nosocomial meningitis, and utility of lumbar puncture, is unclear in hospitalized patients without preceding neurosurgery or head trauma.
David Granton, Joseph Brown, Shannon M. Fernando, Dipayan Chaudhuri, Isaac I. Bogoch, Christine Soong, Marina Englesakis, Bram Rochwerg, Eddy Fan   +8 more
doaj   +1 more source

Pneumorrhachis Following Lumbar Puncture: A Case Report

Kaohsiung Journal of Medical Sciences, 2006
We report a rare case of pneumorrhachis following lumbar puncture. A 4-year-old boy was admitted to our hospital with seizures following a head injury and upper respiratory infection.
Lung-Chang Lin, Yu-Mei Liao, Rei-Cheng Yang   +2 more
doaj   +1 more source

Cerebrospinal Fluid Tau, p-Tau 181 and Amyloid-beta(38/40/42) in Frontotemporal Dementias and Primary Progressive Aphasias [PDF]

, 2010
Background/Aims: We determined cerebrospinal fluid (CSF) concentrations of amyloid-beta(A beta)(1-38), A beta(1-40), A beta(1-42), total tau and phospho-tau (p-tau) in order to study their differential expression in frontotemporal dementia (FTD, n = 25 ...
Bibl, Mirko, Esselmann, Hermann, Kornhuber, Johannes, Lewczuk, Piotr, Mollenhauer, Brit, Otto, Markus, Rüther, Eckart, Wiltfang, Jens, Wolf, Stefanie   +8 more
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Incidence and risk factors of postdural puncture headache: prospective cohort study design

Perioperative Medicine, 2020
Background Postdural puncture headache is one of the complications following spinal anesthesia and accidental dural puncture. Several modifiable risk factors contribute to the development of headache after lumbar puncture, which includes needle size ...
Bedilu Girma Weji, Mohammed Suleiman Obsa, Kidest Getu Melese, Gedion Asnake Azeze   +3 more
doaj   +1 more source

Using a novel virtual-reality simulator to assess performance in lumbar puncture: a validation study

BMC Medical Education, 2023
Background A lumbar puncture procedure’s success depends on a competent physician minimizing the risk of failing to get a sample and avoiding complications such as post-dural headache.
Sujun Xie, Søren Grimstrup, Leizl Joy Nayahangan, Zheng Wang, Xing Wan, Lars Konge   +5 more
doaj   +1 more source

The puncture methods of extrapedicular PVP (PKP): A narrative review

Interdisciplinary Neurosurgery, 2021
Backgroud: A variety of extrapedicular puncture methods have been successfully used in percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP). Currently, there are no reviews on extrapedicular puncture. Authors reviewed the puncture methods
Hong Zhang, Bin Zhao, Lei Luo, Pei Li, Chen Zhao, Dianming Jiang, Qiang Zhou, Liehua Liu   +7 more
doaj   +1 more source

Cryptococcal infection of the ventriculoperitoneal shunt in an immunocompetent patient [PDF]

, 2016
Patient: Male, 52 Final Diagnosis: Cryptococcal ventriculoperitoneal shunt infection Symptoms: Confusion • fever • Lethargy Medication: Amphotericin B • Flucytosine Clinical Procedure: Ventriculoperitoneal shunt removal Specialty: Infectious disease ...
Foong, Kap Sum, Lee, Ashley, Vasquez, Gustavo   +2 more
core   +2 more sources