Results 111 to 120 of about 173,245 (314)

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

Concomitant Lumbar Spine Pathology in Patients Undergoing Hip Arthroscopy: A Matched Cohort Analysis

Orthopaedic Journal of Sports Medicine, 2017
Objectives: Hip arthroscopy for femoroacetabular impingement (FAI) and related hip pathology is increasing in volume. Variable presentations of hip pain often lead to confusion with lumbar spine pathology however.
Siddharth Ashok Mahure MD, MBA, Michael K. Ryan MD, Aaron Buckland MD, FRACS, Mathew Hamula BA, BS, John Begly, Brian Capogna MD, Chris Looze MD, Kristofer E. Chenard MD, Theodore Wolfson BS, Thomas Youm MD   +9 more
doaj   +1 more source

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

The Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen, Emma Sherratt, Philip Stott, Rachel Norris   +3 more
wiley   +1 more source

Morphological variation in atlas and axis of Neotropical spiny rats (Rodentia, Echimyidae)

The Anatomical Record, EarlyView.
Abstract The unique morphologies of the first two cervical vertebrae, the atlas and axis, represent a significant innovation in mammalian evolution. These structures support the weight of the head and enable intricate movements of the head and neck.
Thomas Furtado da Silva Netto, João Felipe Leal Kaiuca, Adriana Itatí Olivares, William Corrêa Tavares   +3 more
wiley   +1 more source

Patterns of spinal motion, kinematic spaces and the land‐to‐sea transition in carnivorans

The Anatomical Record, EarlyView.
Using 3D reconstructions, we quantify intervertebral joint mobility to investigate how cervical, thoracic, and lumbar vertebral regions evolved distinct kinematic roles in pinnipeds. The findings reveal lineage‐specific adaptations for swimming and highlight the functional significance of vertebral joint flexibility in ecological transitions.
Juan Miguel Esteban, Alberto Martín‐Serra, Alejandro Pérez‐Ramos, Borja Figueirido   +3 more
wiley   +1 more source

Drivers of tail evolution in squamates and their implications for the fossorial origin of snakes

The Anatomical Record, EarlyView.
Abstract The axial skeleton serves as the primary structural support in all vertebrates and is subdivided into five distinct regions: cervical, thoracic, lumbar, sacral, and caudal. Relaxation of constraints acting on the terminal end of the axial skeleton has led to remarkable variation in caudal vertebrae number across Squamata.
Olivia Binfield, Marco Camaiti, Lucy Roberts   +2 more
wiley   +1 more source

The biology of the ovine functional spinal unit: facet cartilage and intervertebral disc [PDF]

, 2013
Back pain will affect up to 84 % of people at some point in their lives. It is a major public health problem in Western society leading to disability and economic loss through work absence, physician visits and hospitalisation.
Gough, Caroline Shanni
core  

Comparison of Anterior Spinal Bridging and Sagittal Spinal Parameters in Diffuse Idiopathic Skeletal Hyperostosis and Axial Spondylitis: A Multicenter Study

Spine Surgery and Related Research
Introduction: To evaluate the differences in anterior spinal bridging and sagittal spinal parameters between patients with diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole-spine computed tomography (CT). Methods:
Takuya Takahashi, Kanji Mori, Shigeto Kobayashi, Hisashi Inoue, Kurisu Tada, Naoto Tamura, Takashi Hirai, Yu Matsukura, Satoru Egawa, Satoshi Tamura, Narihito Nagoshi, Satoshi Maki, Keiichi Katsumi, Masao Koda, Kazuma Murata, Kazuhiro Takeuchi, Hiroaki Nakashima, Shiro Imagama, Yoshiharu Kawaguchi, Toshitaka Yoshii   +19 more
doaj   +1 more source

The fossil record stays silent: Confusions and conundrums for hominin pelvis evolution

The Anatomical Record, EarlyView.
Abstract The evolution of the hominin pelvis is commonly modeled as a series of stages driven largely by the requirements of bipedal locomotion, reproduction, thermoregulation, and pelvic floor muscular support. These patterns are complicated by variation in canal dimensions in relationship with different changes in overall pelvic breadths. To quantify
Helen K. Kurki, Cara M. Wall‐Scheffler
wiley   +1 more source

Biomechanical experimental studies of the lumbar spine under static and dynamic loading conditions [PDF]

, 2013
During the past decades the number of spinal injuries has increased. Traffic accidents are the cause of more than 50 per cent of these injuries. Fractures and dislocations of the vertebrae as well as minor spinal injuries can cause both acute and chronic
Osvalder, Anna-Lisa,
core