Results 121 to 130 of about 253,518 (312)

Comparison of Anterior Spinal Bridging and Sagittal Spinal Parameters in Diffuse Idiopathic Skeletal Hyperostosis and Axial Spondylitis: A Multicenter Study

Spine Surgery and Related Research
Introduction: To evaluate the differences in anterior spinal bridging and sagittal spinal parameters between patients with diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole-spine computed tomography (CT). Methods:
Takuya Takahashi, Kanji Mori, Shigeto Kobayashi, Hisashi Inoue, Kurisu Tada, Naoto Tamura, Takashi Hirai, Yu Matsukura, Satoru Egawa, Satoshi Tamura, Narihito Nagoshi, Satoshi Maki, Keiichi Katsumi, Masao Koda, Kazuma Murata, Kazuhiro Takeuchi, Hiroaki Nakashima, Shiro Imagama, Yoshiharu Kawaguchi, Toshitaka Yoshii   +19 more
doaj   +1 more source

Instrumented Lumbar Corpectomy and Spinal Reconstruction Comparing rhBMP-2/Compression-Resistant Matrix, rhBMP-2/Absorbable Collagen Sponge/Ceramic Granules Mixture, and Autograft in Two Different Devices: A Study in Sheep [PDF]

, 2016
Study Design. Fusion success with rhBMP-2 and autograft in titanium or PEEK corpectomy devices was evaluated in a sheep lumbar corpectomy model. The 6 treatment groups included titanium mesh or PEEK corpectomy devices filled with rhBMP-2 on a compression-
Mobasser, Jean-Piere, Schwartz, David G., Toth, Jeffrey M., Williams, Joseph   +3 more
core   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Bioresorbable Film for the Prevention of Adhesion to the Anterior Spine After Anterolateral Discectomy [PDF]

, 2009
Background context The development of scar tissue and adhesions postoperatively is a natural consequence of healing but can be associated with medical complications and render reoperation difficult.
Klopp, Lisa S., Rao, Sangeeta, Tai, Joseph W., Thomas, Kevin A., Toth, Jeffrey M., Turner, Simon, Welch, William C.   +6 more
core   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Bioinspired Fabric Ligament with Tunable Stiffness for Reproducing 3D Lumbar Spine Kinematics

Small Structures
Lumbar spine ligaments play a critical role in maintaining spine joint stability and structural integrity within segmental biomechanics. However, most existing lumbar spine models and simulators neglect ligament contributions, leading to incomplete or ...
Guangsheng Song, Weilong Jin, Guanghui Li, Yushan Sun, Jianan Wu, Hounan Song, Yuyang Wei, Kaize Wang, Zhende Jiang, Zhihui Qian, Lei Ren, Luquan Ren   +11 more
doaj   +1 more source

Polyetheretherketone as a Biomaterial for Spinal Applications [PDF]

, 2006
Threaded lumbar interbody spinal fusion devices (TIBFD) made from titanium have been reported to be 90% effective for single-level lumbar interbody fusion, although radiographic determination of fusion has been intensely debated in the literature.
Estes, Bradley T., Scifert, Jeffrey L., Seim, Howard B., Toth, Jeffrey M., Turner, A. Simon, Wang, Mei   +5 more
core   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Lumbar offset distance: A simplified metric for evaluation of the lumbar spine alignment

Journal of Craniovertebral Junction and Spine
Background: A healthy lower back is essential for optimal spinal function and overall wellness. Magnetic resonance imaging (MRI) has become the gold standard in assessing lumbar spine disease.
Kapil Shirodkar, Sai Niharika Gavvala, Sisith Ariyaratne, Nathan Jenko, Neha Nischal, Karthikeyan P. Iyengar, Jwalant Mehta, Rajesh Botchu   +7 more
doaj   +1 more source

Severe Lumbar Disability Is Associated With Decreased Psoas Cross-Sectional Area in Degenerative Spondylolisthesis [PDF]

, 2018
Study Design: Retrospective cohort. Objectives: Alterations in lumbar paraspinal muscle cross-sectional area (CSA) may correlate with lumbar pathology.
Butler, Joseph S., Kaye, Ian D., Kepler, Christopher K., McKenzie, James C., Morrissey, Patrick B., Sebastian, Arjun S., Vaccaro, Alexander R., Wagner, Scott C.   +7 more
core   +1 more source