Results 141 to 150 of about 434,399 (248)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Microcystic/Reticular Schwannoma Occurring in the Lumbar Spine: A Rare Case Report. [PDF]

Ann Afr Med
Yadav R, Agarwal P, Sagar M.
europepmc   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Patient Experiences of Perioperative Care in Lumbar Spine Surgery: A Qualitative Study. [PDF]

Nurs Open
Petrucci G, Vadalà G, Russo F, Maltese G, Papalia R, Denaro V.   +5 more
europepmc   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Lumbar Spine Motion Analysis: A Systematic Review of Segmental and Global Range of Motion. [PDF]

Cureus
Tan QH, Aurangzeb A, Mohamad H, Leong D, Kumar D, Janssen ME, Chew Z.   +6 more
europepmc   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

Clinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo, Shuhei Shiino, Stephen Z. Shapiro, Brianna L. Hines, Noritaka Komune, Carmine Antonio Donofrio, Filippo Badaloni, Antonio Fioravanti, Joseph Lockwood, C. J. Bui, Aaron S. Dumont, R. Shane Tubbs   +11 more
wiley   +1 more source

Methodological Considerations in Evaluating Preoperative Physiotherapy for Lumbar Spine Surgery. [PDF]

Physiother Res Int
Nahak PK.
europepmc   +1 more source

Serum uric acid is associated with lumbar spine bone mineral density in healthy Chinese males older than 50 years

, 2017
Jing Xiao, Weijun Chen, Xinhui Feng, Wenyi Liu, Zhenxing Zhang, Li He, Zhibin Ye Department of Nephrology, Huadong Hospital Affiliated to Fudan University, Shanghai, People’s Republic of China Objectives: We aimed to investigate the association ...
Feng XH, Xiao J, Liu WY, Zhang ZX, Ye ZB, He L, Chen WJ   +6 more
core  

The Cutaneous Branch of the Obturator Nerve: Common Finding or a Rarity Worthy of Note

Clinical Anatomy, EarlyView.
ABSTRACT According to textbook descriptions, branches of the femoral and obturator nerves provide the sensory innervation to the medial side of the thigh. However, as the exact prevalence of the obturator nerve's cutaneous branch is unknown, an anatomic study was conducted to reveal its role in providing cutaneous innervation to the medial thigh ...
Christoph Fuchssteiner, Theresia Stigger, Gerlinde M. Gruber, Peter. C. Brugger   +3 more
wiley   +1 more source