Results 71 to 80 of about 175,035 (289)
A Rare Foramen at the Base of the Transverse Process of the Fourth Lumbar Vertebra
National Journal of Clinical AnatomyA 58-year-old male presented with paraplegia of the lower limbs due to a burst fracture of the first lumbar vertebra following a road traffic accident.
Raju Paul Manjooran
doaj +1 more source
Advanced Science, EarlyView.The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma +12 more
wiley +1 more source
Congenital malformation of fifth lumbar vertebra: A case report [PDF]
, 2017 Fifth lumbar vertebra is an atypical vertebra as it has widely separated inferior articular processes and thick transverse processes projecting out from the body and pedicles of the vertebra. On routine examination of osteology specimens we found a fifth
Chauhan, Renu, Khanna, Jugesh
core
Advanced Science, EarlyView.Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng +7 more
wiley +1 more source
, 2017 Objectives: Three issues are considered on variation in number of presacral vertebrae (PSV) in humans: (1) sexual difference in number of PSV, (2) inactivation of Hoxd-11 gene as etiology for a supernumerary lumbar vertebra, and (3) anatomical correlates
Tague, Robert G., Robert G. Tague
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Advanced Science, EarlyView.This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu +12 more
wiley +1 more source
Case Reports in Endocrinology, 2012 We report the case of a 66-year-old woman with tumor-induced osteomalacia (TIO) caused by fibroblast growth factor 23 (FGF-23) secreting mesenchymal tumor localized in a lumbar vertebra and review other cases localized to the axial skeleton.
Gunjan Y. Gandhi +4 more
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Advanced Intelligent Systems, EarlyView.This review traces three decades of technological evolution in robot‐assisted fracture reduction systems, from early robotic concepts to clinically oriented platforms. Key advances in robotic architecture, navigation, path planning, interaction control, and surgical integration are summarized, while current translational challenges and future ...
Shaolong Kuang +5 more
wiley +1 more source
An unusual case of dorsally sequestrated disk mimicking tumor with cauda equina syndrome
Journal of Spinal Surgery, 2016 A 44-year-old male presented with acute onset retention of urine and low back pain. Magnetic resonance imaging (MRI) of the lumbar spine demonstrated an extradural mass extending from the lower border of the L3 vertebra to upper border of L5 vertebra ...
Batuk Damjibhai Diyora +4 more
doaj +1 more source
Severe Phenotype in an Indian Family With Progressive Pseudorheumatoid Arthropathy of Childhood
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Progressive pseudorheumatoid arthropathy of childhood (PPAC) is a rare autosomal recessive progressive condition that affects the cartilage of joints and bones. The symptoms of PPAC include stiffness of the joints, bony swelling of the toes and fingers, short stature, kyphosis, and muscle weakness.
Narinder Singh +5 more
wiley +1 more source