Results 41 to 50 of about 58,474 (256)
Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain
Advanced Science, EarlyView.Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh +7 more
wiley +1 more source
Morphometric substantiation of a fixation method choice at surgical correction of spondylolisthesis [PDF]
Саратовский научно-медицинский журнал, 2010 The purpose was to reveal patterns of morphometric characteristics variability of lumbar vertebrae and sacrum for a choice of more adequate selection of standard sizes and introduction orientation of corrigent metalware at surgical treatment of ...
Anisimova Е.А. +3 more
doaj
Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis
Advanced Science, EarlyView.Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao +28 more
wiley +1 more source
Anthropological Review, 2023 In European populations, the birth season significantly correlates with many biological features. It is thus possible that the observed clinical effects of bone metabolism disorders are a partial consequence of bone mineral density (BMD), modified by the
Iwona Rosset +4 more
doaj +1 more source
Advanced Science, EarlyView.Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
Scientific Reports, 2022 Standing radiographs play an important role in the characterization of spinal sagittal alignment, as they depict the spine under physiologic loading conditions.
Benjamin Hajnal +6 more
doaj +1 more source
South African Journal of Radiology, 2006 Spinal chordomas in the lumbar region are rare and can easily be overlooked in the differential diagnosis of vertebral column tumours. South African Journal of Radiology Vol. 10 (3) 2006: pp.
A Erlank +5 more
openaire +4 more sources
Advanced Science, EarlyView.This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo +11 more
wiley +1 more source
Biomechanical Evaluation of Compressive Stress in Lumbar Vertebrae – A Pilot Survey
National Journal of Clinical AnatomyBackground: Cadaveric research in orthopedics poses challenges for medical students and early-career professionals due to limited resources, mentorship, and technical support.
Alexander Baur +3 more
doaj +1 more source
An abnormal lumbar vertebra [PDF]
Journal of Comparative Pathology and Therapeutics, 1893 n ...
openaire +2 more sources