Results 61 to 70 of about 51,312 (144)

Shunt surgery and lecanemab therapy in patients with idiopathic normal pressure hydrocephalus and alzheimer’s disease: a report of two cases

open access: yesActa Neurochirurgica
Idiopathic normal pressure hydrocephalus (iNPH) is a condition in the elderly commonly treated with ventriculoperitoneal (VP) or lumboperitoneal (LP) shunt surgery.
Koichi Miyazaki   +2 more
doaj   +1 more source

The contribution of cerebral small vessel disease in idiopathic normal pressure hydrocephalus: Insights from a prospective cohort study

open access: yesAlzheimer's &Dementia, Volume 21, Issue 1, January 2025.
Abstract INTRODUCTION Idiopathic normal pressure hydrocephalus (iNPH) and cerebral small vessel disease (CVSD) are age‐related diseases, but their prevalence and clinical relationship are unclear. METHODS This prospective cohort study enrolled 95 patients with probable iNPH in China and evaluated their CSVD burden using magnetic resonance imaging ...
Hanlin Cai   +16 more
wiley   +1 more source

Shunt Intervention for Possible Idiopathic Normal Pressure Hydrocephalus Improves Patient Outcomes: A Nationwide Hospital-Based Survey in Japan

open access: yesFrontiers in Neurology, 2018
Background and Purpose: This study aimed to investigate the efficacy of cerebrospinal fluid shunt intervention for idiopathic normal pressure hydrocephalus (iNPH) using data from a nationwide epidemiological survey in Japan.Methods: We conducted a cross ...
Madoka Nakajima   +13 more
doaj   +1 more source

Improvement in the long-term care burden after surgical treatment of patients with idiopathic normal pressure hydrocephalus: a supplementary study

open access: yesScientific Reports, 2021
Idiopathic normal pressure hydrocephalus (iNPH) is a surgically treatable syndrome commonly observed in older adults. However, it is unclear whether clinical improvements after surgery can effectively reduce the long-term care burden (LTCB).
Masatsune Ishikawa   +4 more
doaj   +1 more source

The glymphatic system: A new insight into the understanding of neurological diseases

open access: yesBrain‐X, Volume 2, Issue 4, December 2024.
This review highlights the glymphatic system's role in clearing CNS metabolic waste, involving key structures such as AQP4 channels and meningeal lymphatic vessels. It examines how sleep, arterial pulsation, aging, and drugs affect glymphatic function.
Junbo Liao   +8 more
wiley   +1 more source

Lumboperitoneal shunt insertion without fluoroscopy guidance: Accuracy of placement in a series of 107 procedures

open access: yes, 2017
Background: Lumboperitoneal (LP) shunts were the mainstay of cerebrospinal fluid diversion therapy for idiopathic intracranial hypertension (IIH).
Linda D’Antona   +6 more
core   +1 more source

Clinical magnetic resonance imaging evaluation of glymphatic function

open access: yesNMR in Biomedicine, Volume 37, Issue 8, August 2024.
The glymphatic system is a system of specialized perivascular spaces in the brain that facilitates removal of toxic waste solutes from the brain. This review discusses MRI methods that can be employed clinically for glymphatic‐related measurements intended for early diagnosis, prevention, and the treatment of various neurological conditions.
Edward D. Boyd   +4 more
wiley   +1 more source

Progress and recognition of idiopathic intracranial hypertension: A narrative review

open access: yesCNS Neuroscience &Therapeutics, Volume 30, Issue 8, August 2024.
We integrate recent studies and findings to provide a thorough and detailed exploration of various facets of idiopathic intracranial hypertension, including its epidemiology, pathophysiological mechanisms, clinical features, and treatment strategies. This contributes to a better understanding of the disease and potential therapeutic targets.
Chenxia Zhou   +6 more
wiley   +1 more source

Clinical outcome of cerebrospinal fluid shunts in patients with leptomeningeal carcinomatosis

open access: yesWorld Journal of Surgical Oncology, 2019
Background Leptomeningeal carcinomatosis (LMC) is frequently associated with hydrocephalus, which quickly devastates the performance of the patient. Cerebrospinal fluid (CSF) shunt is a widely accepted treatment of choice, but the clinical outcomes in ...
Hye Seon Kim   +5 more
doaj   +1 more source

Pseudotumor cerebri with status epilepticus in a child: A rare presentation of vitamin D deficiency

open access: yesClinical Case Reports, Volume 12, Issue 4, April 2024.
Key Clinical Message Pseudotumor cerebri (PTC) encompasses a constellation of symptoms caused by elevated intracranial pressure of unclear etiology. Various associations have been described, rarely hypovitaminosis D. Vitamin D deficiency should be considered as a potential etiology of neurological manifestations like PTC and seizures in children. Early
Soumya Pahari   +4 more
wiley   +1 more source

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