Results 61 to 70 of about 1,287,560 (260)

Re-expansion of Thrombosed False Lumen after Aortic Dissection Due to Collateral Retrograde Flow from the Aortic Branches

Annals of Vascular Diseases, 2021
Re-expansion of thrombosed false lumen after aortic dissection due to collateral retrograde flow from the aortic branches has rarely been reported. Surgical or endovascular local management such as ligation or occlusion of culprit arteries may not be effective in case retrograde blood flow to the false lumen might occur again from another branch after ...
Hamuro, Mamoru, Miwa, Senri, Yamamoto, Kenji, Enomoto, Sakae   +3 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Biomechanical control of vascular morphogenesis by the surrounding stiffness

Nature Communications
Sprouting angiogenesis is a form of morphogenesis which expands vascular networks from preexisting networks. However, the precise mechanism governing efficient branch elongation driven by directional movement of endothelial cells (ECs), while the lumen ...
Yasuyuki Hanada, Semanti Halder, Yuichiro Arima, Misato Haruta, Honami Ogoh, Shuntaro Ogura, Yukihiko Shiraki, Sota Nakano, Yuka Ozeki, Shigetomo Fukuhara, Akiyoshi Uemura, Toyoaki Murohara, Koichi Nishiyama   +12 more
doaj   +1 more source

Transcatheter electrosurgical septotomy technique for chronic postdissection aortic aneurysms

Journal of Vascular Surgery Cases and Innovative Techniques
Aortic dissection often results in chronic aneurysmal degeneration due to progressive false lumen expansion. Thoracic endovascular aortic repair and other techniques of vessel incorporation such as fenestrated-branched or parallel grafts have been ...
Aidin Baghbani-Oskouei, MD, Safa Savadi, MD, Thomas Mesnard, MD, Titia Sulzer, BSc, Aleem K. Mirza, MD, Shadman Baig, MD, Carlos H. Timaran, MD, Gustavo S. Oderich, MD   +7 more
doaj   +1 more source

Cell volume changes contribute to epithelial morphogenesis in zebrafish Kupffer’s vesicle

eLife, 2018
How epithelial cell behaviors are coordinately regulated to sculpt tissue architecture is a fundamental question in biology. Kupffer’s vesicle (KV), a transient organ with a fluid-filled lumen, provides a simple system to investigate the interplay ...
Agnik Dasgupta, Matthias Merkel, Madeline J Clark, Andrew E Jacob, Jonathan Edward Dawson, M Lisa Manning, Jeffrey D Amack   +6 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Effect of Crack Patterns in Calcified Plaque on Lumen Area after Stenting for a Severe Calcified Coronary Artery (from the Optical Frequency Domain Imaging-Guided Percutaneous Coronary Artery Intervention for Calcified Lesion Registry)

Journal of Interventional Cardiology, 2022
Background. Severely calcified coronary artery stenting remains a challenge due to stent thrombosis, target vessel failure, and higher mortality. Moreover, optimal vessel preparation for calcified plaque with a crack formation pattern has not been ...
Hirooki Higami, Hiroaki Matsuda, Hikaru Tateyama, Yoriyasu Suzuki, Kazuaki Kaitani   +4 more
doaj   +1 more source

Comparison of small lumen versus large lumen inter costal catheter drainage in empyema thoracis on degree of comfort and re-expansion of lungs: An open label, quasi randomized study

Clinical Epidemiology and Global Health, 2022
Background: Use of intercostal drainage tube (ICDT) is an accepted treatment of empyema thoracis (ET).We compared the effectiveness of small versus large lumen ICDT on degree of pain on 4th day of ICDT insertion as well as drainage of pus in cases of ET.
Sunil Kumar, Shally Awasthi, Nishant Verma, Sarika Gupta   +3 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source