Results 1 to 10 of about 378,865 (268)

Orchestration an extracellular lipase production from Aspergillus niger MYA 135: biomass morphology and fungal physiology

AMB Express, 2021
The impact of biomass morphology and culture conditions on fungal fermentation was widely reviewed in the literature. In this work, we presented three independent experiments in order to evaluate the influence of some of those input factors on a lipase ...
Hebe Natalia Salvatierra, Erika Lucía Regner, Mario Domingo Baigorí, Licia María Pera   +3 more
doaj   +1 more source

Comparative analysis of liver involvement caused by two DENV-2 lineages using an immunocompetent murine model

Scientific Reports, 2021
Dengue (DEN) is the most prevalent arbovirus among humans, and four billion people live at risk of infection. The clinical manifestations of DEN are variable, and the disease may present subclinically or asymptomatically.
Fernanda Cunha Jácome, Gabriela Cardoso Caldas, Arthur da Costa Rasinhas, Ana Luisa Teixeira de Almeida, Daniel Dias Coutinho de Souza, Amanda Carlos Paulino, Raphael Leonardo, Ortrud Monika Barth, Flavia Barreto dos Santos, Débora Ferreira Barreto-Vieira   +9 more
doaj   +1 more source

Targeted mechanical stimulation via magnetic nanoparticles guides in vitro tissue development

Nature Communications, 2023
Tissues take shape through a series of morphogenetic movements guided by local cell-scale mechanical forces. Current in vitro approaches to recapitulate tissue mechanics rely on uncontrolled self-organization or on the imposition of extrinsic and ...
Abdel Rahman Abdel Fattah, Niko Kolaitis, Katrien Van Daele, Brian Daza, Andika Gregorius Rustandi, Adrian Ranga   +5 more
doaj   +1 more source

High-Throughput Imaging of Blood Flow Reveals Developmental Changes in Distribution Patterns of Hemodynamic Quantities in Developing Zebrafish

Frontiers in Physiology, 2022
Mechanical forces from blood flow and pressure (hemodynamic forces) contribute to the formation and shaping of the blood vascular network during embryonic development. Previous studies have demonstrated that hemodynamic forces regulate signaling and gene
Swe Soe Maung Ye, Jung Kyung Kim, Jung Kyung Kim, Nuria Taberner Carretero, Li-Kun Phng   +4 more
doaj   +1 more source

Competitive PCR with dual fluorescent primers enhances the specificity and reproducibility of genotyping animals generated from genome editing

Cell & Bioscience, 2023
Targeted genome editing is a powerful tool for studying gene function in almost every aspect of biological and pathological processes. The most widely used genome editing approach is to introduce engineered endonucleases or CRISPR/Cas system into cells ...
Liezhen Fu, Emily Ma, Morihiro Okada, Yuki Shibata, Yun-Bo Shi   +4 more
doaj   +1 more source

Regional specialization and fate specification of bone stromal cells in skeletal development

Cell Reports, 2021
Summary: Bone stroma contributes to the regulation of osteogenesis and hematopoiesis but also to fracture healing and disease processes. Mesenchymal stromal cells from bone (BMSCs) represent a heterogenous mixture of different subpopulations with ...
Kishor K. Sivaraj, Hyun-Woo Jeong, Backialakshmi Dharmalingam, Dagmar Zeuschner, Susanne Adams, Michael Potente, Ralf H. Adams   +6 more
doaj   +1 more source

Immunocompetent Mice Infected by Two Lineages of Dengue Virus Type 2: Observations on the Pathology of the Lung, Heart and Skeletal Muscle

Microorganisms, 2021
Dengue virus (DENV) infection by one of the four serotypes (DENV-1 to 4) may result in a wide spectrum of clinical manifestations, with unpredictable evolution and organ involvement.
Fernanda Cunha Jácome, Gabriela Cardoso Caldas, Arthur da Costa Rasinhas, Ana Luisa Teixeira de Almeida, Daniel Dias Coutinho de Souza, Amanda Carlos Paulino, Marcos Alexandre Nunes da Silva, Derick Mendes Bandeira, Ortrud Monika Barth, Flavia Barreto dos Santos, Debora Ferreira Barreto-Vieira   +10 more
doaj   +1 more source

The transpeptidase PBP2 governs initial localization and activity of the major cell-wall synthesis machinery in E. coli

eLife, 2020
Bacterial shape is physically determined by the peptidoglycan cell wall. The cell-wall-synthesis machinery responsible for rod shape in Escherichia coli is the processive 'Rod complex'.
Gizem Özbaykal, Eva Wollrab, Francois Simon, Antoine Vigouroux, Baptiste Cordier, Andrey Aristov, Thibault Chaze, Mariette Matondo, Sven van Teeffelen   +8 more
doaj   +1 more source

Morphological Aspects and Viremia Analysis of BALB/c Murine Model Experimentally Infected with Dengue Virus Serotype 4

Viruses, 2021
Ever since its brief introduction in the Brazilian territory in 1981, dengue virus serotype 4 (DENV-4) remained absent from the national epidemiological scenario for almost 25 years. The emergence of DENV-4 in 2010 resulted in epidemics in most Brazilian
Arthur da Costa Rasinhas, Fernanda Cunha Jácome, Gabriela Cardoso Caldas, Ana Luisa Teixeira de Almeida, Marcos Alexandre Nunes da Silva, Daniel Dias Coutinho de Souza, Amanda Carlos Paulino, Derick Mendes Bandeira, Raphael Leonardo, Priscila Conrado Guerra Nunes, Ronaldo Mohana-Borges, Ortrud Monika Barth, Flavia Barreto dos Santos, Debora Ferreira Barreto Vieira   +13 more
doaj   +1 more source

Distinct molecular cues ensure a robust microtubule-dependent nuclear positioning in the Drosophila oocyte

Nature Communications, 2017
Asymmetric nuclear positioning in the fruit fly oocyte is essential for the correct localization of axis determinants. Here, the authors show that different microtubule-dependent mechanisms contribute to nuclear transport and ensure the robustness of ...
Nicolas Tissot, Jean-Antoine Lepesant, Fred Bernard, Kevin Legent, Floris Bosveld, Charlotte Martin, Orestis Faklaris, Yohanns Bellaïche, Maïté Coppey, Antoine Guichet   +9 more
doaj   +1 more source