Echocardiographic assessment of Xenopus tropicalis heart regeneration [PDF]
Cell & Bioscience, 2023 Background Recently, it was reported that the adult X. tropicalis heart can regenerate in a nearly scar-free manner after injury via apical resection. Thus, a cardiac regeneration model in adult X. tropicalis provides a powerful tool for recapitulating a
Luocheng Lv +13 more
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Evolutionary divergence in tail regeneration between Xenopus laevis and Xenopus tropicalis [PDF]
Cell & Bioscience, 2021 Tissue regeneration is of fast growing importance in the development of biomedicine, particularly organ replacement therapies. Unfortunately, many human organs cannot regenerate.
Shouhong Wang, Yun-Bo Shi
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A comparative analysis of transcription factor expression during metazoan embryonic development. [PDF]
PLoS ONE, 2013 During embryonic development, a complex organism is formed from a single starting cell. These processes of growth and differentiation are driven by large transcriptional changes, which are following the expression and activity of transcription factors ...
Alicia N Schep, Boris Adryan
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CRISPR/Cas-mediated mRNA knockdown in the embryos of Xenopus tropicalis [PDF]
Cell & BioscienceThe Xenopus tropicalis (Western clawed frog) is an important amphibian model for genetics, developmental and regenerative biology, due to its diploid genetic background and short generation time.
Xiao-Lin Lin +13 more
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Cardiomyocyte proliferation and heart regeneration in adult Xenopus tropicalis evidenced by a transgenic reporter line [PDF]
npj Regenerative MedicineCardiomyocyte proliferation in adult Xenopus tropicalis during heart regeneration has remained largely contentious due to the absence of genetic evidence.
Xiao-Lin Lin +8 more
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Developing immortal cell lines from Xenopus embryos, four novel cell lines derived from Xenopus tropicalis [PDF]
Open Biology, 2022 The diploid anuran Xenopus tropicalis has emerged as a key research model in cell and developmental biology. To enhance the usefulness of this species, we developed methods for generating immortal cell lines from Nigerian strain (NXR_1018, RRID ...
Gary J. Gorbsky +8 more
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Identification of tumor-related genes via RNA sequencing of tumor tissues in Xenopus tropicalis [PDF]
Scientific Reports, 2023 Cancer treatment is still challenging because the disease is often caused by multiple mutations. Although genomic studies have identified many oncogenes and tumor suppressor genes, gene sets involved in tumorigenesis remain poorly understood.
Kazuki Kitamura +9 more
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Xenopus Hybrids Provide Insight Into Cell and Organism Size Control [PDF]
Frontiers in Physiology, 2018 Determining how size is controlled is a fundamental question in biology that is poorly understood at the organismal, cellular, and subcellular levels. The Xenopus species, X. laevis and X. tropicalis differ in size at all three of these levels.
Romain Gibeaux +4 more
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Melanin deposition and key molecular features in Xenopus tropicalis oocytes [PDF]
BMC BiologyBackground Melanin pigmentation in oocytes is a critical feature for both the esthetic and developmental aspects of oocytes, influencing their polarity and overall development.
Hongyang Yi +11 more
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Metamorphic gene regulation programs in Xenopus tropicalis tadpole brain [PDF]
PLoS ONE, 2023 Amphibian metamorphosis is controlled by thyroid hormone (TH), which binds TH receptors (TRs) to regulate gene expression programs that underlie morphogenesis.
Samhitha Raj +3 more
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