African clawed frogs, genus Xenopus, are extraordinary among vertebrates in the diversity of their polyploid species and the high number of independent polyploidization events that occurred during their diversification.
Ben J Evans +11 more
doaj +1 more source
Suv4-20h Histone Methyltransferases Promote Neuroectodermal Differentiation by Silencing the Pluripotency-Associated Oct-25 Gene [PDF]
Post-translational modifications (PTMs) of histones exert fundamental roles in regulating gene expression. During development, groups of PTMs are constrained by unknown mechanisms into combinatorial patterns, which facilitate transitions from uncommitted
A Barski +57 more
core +3 more sources
Characterization of Pax3 and Sox10 Transgenic Xenopus Laevis Embryos as Tools to Study Neural Crest Development [PDF]
The neural crest is a multipotent population of cells that originates a variety of cell types. Many animal models are used to study neural crest induction, migration and differentiation, with amphibians and birds being the most widely used systems.
Alkobtawi, Mansour +7 more
core +2 more sources
The Immunoglobulins of Cold-Blooded Vertebrates [PDF]
Peer reviewedPublisher ...
Chen +22 more
core +2 more sources
Remobilization of Tol2 transposons in Xenopus tropicalis [PDF]
Abstract Background The Class II DNA transposons are mobile genetic elements that move DNA sequence from one position in the genome to another. We have previously demonstrated that the naturally occurring Tol2 element from Oryzias latipes efficiently integrates its corresponding non-autonomous transposable element ...
Yergeau, Donald A +6 more
openaire +2 more sources
A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus [PDF]
During vertebrate embryogenesis, the cranial neural crest (CNC) forms at the neural plate border and subsequently migrates and differentiates into many types of cells.
Duncan, Melinda K. +7 more
core +1 more source
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]
Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien +12 more
core +2 more sources
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David +8 more
core +3 more sources
htsint: a Python library for sequencing pipelines that combines data through gene set generation [PDF]
Background: Sequencing technologies provide a wealth of details in terms of genes, expression, splice variants, polymorphisms, and other features. A standard for sequencing analysis pipelines is to put genomic or transcriptomic features into a context of
Bonneaud, Camille +2 more
core +3 more sources
Comparative transcriptome reveal the potential adaptive evolutionary genes in Andrias davidianus
To search the evidence of molecular evolution mechanism for aquatic and cave habitat in Andrias davidianus, the evolution analysis was carried out among several species transcriptome data.
Qiaomu Hu +4 more
doaj +1 more source

