Results 41 to 50 of about 15,789 (195)

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]

, 2016
Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien, Colpaert, Robin, Creytens, David, Deforce, Dieter, Dimitrakopoulou, Dionysia, Haustraete, Jurgen, L, J, Lepez, Trees, Naert, Thomas, Steyaert, Wouter, Van Nieuwenhuysen, Tom, Vleminckx, Kris, Willaert, Andy   +12 more
core   +2 more sources

A de novo reference transcriptome for Bolitoglossa vallecula, an Andean mountain salamander in Colombia [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Arenas Gomez, C. M., Woodcock, M. R., Smith, J. J., Voss, S. R., & Delgado, J. P. A de novo reference
Arenas Gómez, Claudia Marcela, Delgado, Jean Paul, Smith, Jeramiah J., Voss, S. Randal, Woodcock, M. Ryan   +4 more
core   +1 more source

Decoding development in Xenopus tropicalis [PDF]

genesis, 2007
AbstractXenopus tropicalis is rapidly being adopted as a model organism for developmental biology research and has enormous potential for increasing our understanding of how embryonic development is controlled. In recent years there has been a well‐organized initiative within the Xenopus community, funded largely through the support of the National ...
Chris, Showell, Frank L, Conlon
openaire   +2 more sources

Genetics, Morphology, Advertisement Calls, and Historical Records Distinguish Six New Polyploid Species of African Clawed Frog (Xenopus, Pipidae) from West and Central Africa.

PLoS ONE, 2015
African clawed frogs, genus Xenopus, are extraordinary among vertebrates in the diversity of their polyploid species and the high number of independent polyploidization events that occurred during their diversification.
Ben J Evans, Timothy F Carter, Eli Greenbaum, Václav Gvoždík, Darcy B Kelley, Patrick J McLaughlin, Olivier S G Pauwels, Daniel M Portik, Edward L Stanley, Richard C Tinsley, Martha L Tobias, David C Blackburn   +11 more
doaj   +1 more source

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]

, 2015
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David, Geurs, Sarah, Naert, Thomas, Sanders, Ellen, Tran Thi, Hong, Van Imschoot, Griet, Van Nieuwenhuysen, Tom, Van Roy, Frans, Vleminckx, Kris   +8 more
core   +3 more sources

A genetic map of Xenopus tropicalis

Developmental Biology, 2011
We present a genetic map for Xenopus tropicalis, consisting of 2886 Simple Sequence Length Polymorphism (SSLP) markers. Using a bioinformatics-based strategy, we identified unique SSLPs within the X. tropicalis genome. Scaffolds from X. tropicalis genome assembly 2.0 (JGI) were scanned for Simple Sequence Repeats (SSRs); unique SSRs were then tested ...
Wells, Dan E., Gutierrez, Laura, Xu, Zhenkang, Krylov, Vladimir, Macha, Jaroslav, Blankenburg, Kerstin P., Hitchens, Matthew, Bellot, Larry J., Spivey, Mary, Stemple, Derek L., Kowis, Andria, Ye, Yuan, Pasternak, Shiran, Owen, Jenetta, Tran, Thu, Slavikova, Renata, Tumova, Lucie, Tlapakova, Tereza, Seifertova, Eva, Scherer, Steven E., Sater, Amy K.   +20 more
openaire   +2 more sources

A zinc transporter gene required for development of the nervous system. [PDF]

, 2013
The essentiality of zinc for normal brain development is well established. It has been suggested that primary and secondary zinc deficiencies can contribute to the occurrence of numerous human birth defects, including many involving the central nervous ...
Chowanadisai, Winyoo, Graham, David M, Keen, Carl L, Messerli, Mark A, Rucker, Robert B   +4 more
core   +1 more source

A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus [PDF]

, 2019
During vertebrate embryogenesis, the cranial neural crest (CNC) forms at the neural plate border and subsequently migrates and differentiates into many types of cells.
Duncan, Melinda K., Li, Jiejing, Li, Rebecca, Materna, Christopher, Perfetto, Mark, Tran Thi, Hong, Vleminckx, Kris, Wei, Shuo   +7 more
core   +1 more source

Generation and Care of Xenopus laevis and Xenopus tropicalis Embryos [PDF]

, 2018
Robust and efficient protocols for fertilization and early embryo care of Xenopus laevis and Xenopus tropicalis are essential for experimental success, as well as maintenance and propagation of precious animal stocks. The rapid growth of the National Xenopus Resource has required effective implementation and optimization of these protocols.
Marcin, Wlizla, Sean, McNamara, Marko E, Horb   +2 more
openaire   +2 more sources

Chromatin immunoprecipitation and deep sequencing in Xenopus tropicalis and Xenopus laevis [PDF]

Methods, 2014
Chromatin immunoprecipitation and deep sequencing (ChIP-SEQ) represents a powerful tool for identifying the genomic targets of transcription factors, chromatin remodeling factors, and histone modifications. The frogs Xenopus laevis and Xenopus tropicalis have historically been outstanding model systems for embryology and cell biology, with emerging ...
Andrea E, Wills, Rakhi, Gupta, Edward, Chuong, Julie C, Baker   +3 more
openaire   +2 more sources