Evolution of aldehyde dehydrogenase genes and proteins in diploid and allotetraploid Xenopus frog species [PDF]
, 2021 At least 19 human aldehyde dehydrogenase (ALDH) genes and enzymes have been studied among vertebrate organisms. BLAT and BLAST analyses were undertaken of Xenopus tropicalis (western clawed frog) and Xenopus laevis (African clawed frog) genomes which are
Holmes, Roger S
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Generation and Care of Xenopus laevis and Xenopus tropicalis Embryos [PDF]
, 2018 Robust and efficient protocols for fertilization and early embryo care of Xenopus laevis and Xenopus tropicalis are essential for experimental success, as well as maintenance and propagation of precious animal stocks. The rapid growth of the National Xenopus Resource has required effective implementation and optimization of these protocols.
Marcin, Wlizla +2 more
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Chromatin immunoprecipitation and deep sequencing in Xenopus tropicalis and Xenopus laevis [PDF]
Methods, 2014 Chromatin immunoprecipitation and deep sequencing (ChIP-SEQ) represents a powerful tool for identifying the genomic targets of transcription factors, chromatin remodeling factors, and histone modifications. The frogs Xenopus laevis and Xenopus tropicalis have historically been outstanding model systems for embryology and cell biology, with emerging ...
Andrea E, Wills +3 more
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CRISPR/Cas9-mediated knockout of Rb1 in Xenopus tropicalis [PDF]
, 2018 At this time, no molecular targeted therapies exist for treatment of retinoblastoma. This can be, in part, attributed to the lack of animal models that allow for both rapid identification of novel therapeutic targets and hypothesis driven drug testing ...
Naert, Thomas +3 more
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A Xenopus tropicalis oligonucleotide microarray works across species using RNA from Xenopus laevis [PDF]
, 2004 Microarrays have great potential for the study of developmental biology. As a model system Xenopus is well suited for making the most of this potential.
Chalmers, Andrew D. +11 more
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Suv4-20h Histone Methyltransferases Promote Neuroectodermal Differentiation by Silencing the Pluripotency-Associated Oct-25 Gene [PDF]
, 2013 Post-translational modifications (PTMs) of histones exert fundamental roles in regulating gene expression. During development, groups of PTMs are constrained by unknown mechanisms into combinatorial patterns, which facilitate transitions from uncommitted
Jung, Julia +23 more
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Xenopus Hybrids Provide Insight Into Cell and Organism Size Control
Frontiers in Physiology, 2018 Determining how size is controlled is a fundamental question in biology that is poorly understood at the organismal, cellular, and subcellular levels. The Xenopus species, X. laevis and X. tropicalis differ in size at all three of these levels.
Romain Gibeaux +4 more
doaj +1 more source
Comparative transcriptome reveal the potential adaptive evolutionary genes in Andrias davidianus
Hereditas, 2018 To search the evidence of molecular evolution mechanism for aquatic and cave habitat in Andrias davidianus, the evolution analysis was carried out among several species transcriptome data.
Qiaomu Hu +4 more
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Picroscope: low-cost system for simultaneous longitudinal biological imaging
Communications Biology, 2021 Ly et al. report a multi-well imaging system (the Picroscope) that can perform longitudinal bright-field z-stack imaging for 24 wells simultaneously. They demonstrate its capability by imaging zebrafish embryos, planaria worms, development of Xenopus ...
Victoria T. Ly +18 more
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Identification of REST targets in the Xenopus tropicalis genome [PDF]
BMC Genomics, 2015 A major role of REST (repressor element-1 silencing transcription factor) is to inhibit the expression of neuronal genes in neural stem cells and non-neuronal cells by binding to a 21 bp consensus sequence and recruiting epigenetic and regulatory cofactors to gene regulatory regions.
Saritas-Yildirim, Banu +3 more
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