Results 71 to 80 of about 15,789 (195)

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Is adult cardiac regeneration absent in Xenopus laevis yet present in Xenopus tropicalis?

open access: yesCell & Bioscience, 2018
We recently used an endoscopy-based resection method to explore the consequences of cardiac injury in adult Xenopus laevis, obtaining the result that the adult Xenopus heart is unable to regenerate.
Lindsey Marshall   +3 more
doaj   +1 more source

Production of Xenopus tropicalis Egg Extracts to Identify Microtubule-associated RNAs [PDF]

open access: yes, 2014
Many organisms localize mRNAs to specific subcellular destinations to spatially and temporally control gene expression. Recent studies have demonstrated that the majority of the transcriptome is localized to a nonrandom position in cells and embryos. One
Blower, Mike D., Sharp, Judith A.
core   +1 more source

Secretopathies emerge as a new class of neurocristopathies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira   +3 more
wiley   +1 more source

Metabolomic approach for identifying and visualizing molecular tissue markers in tadpoles of Xenopus tropicalis by mass spectrometry imaging

open access: yesBiology Open, 2016
In developmental and cell biology it is crucial to evaluate the dynamic profiles of metabolites. An emerging frog model system using Xenopus tropicalis, whose genome sequence and inbred strains are available, is now ready for metabolomics investigation ...
Naoko Goto-Inoue   +3 more
doaj   +1 more source

An optimized method for cryogenic storage of Xenopus sperm to maximise the effectiveness of research using genetically altered frogs [PDF]

open access: yes, 2017
© The Author(s), 2017. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Theriogenology 92 (2017): 149–155, doi:10.1016/j.theriogenology.2017.01.007.Cryogenic storage of sperm
Guille, Matthew   +5 more
core   +2 more sources

Whole tissue imaging of cellular boundaries at sub‐micron resolutions for deep learning cell segmentation: Applications in the analysis of epithelial bending of ectoderm

open access: yesDevelopmental Dynamics, Volume 255, Issue 5, Page 503-521, May 2026.
Abstract Background To understand cellular morphology, biologists have relied on traditional optical microscopy of tissues combined with tissue clearing protocols to image structures deep within tissues. Unfortunately, these protocols often struggle to retain cell boundary markers, especially at high enough resolutions necessary for precise cell ...
Sam C. P. Norris   +2 more
wiley   +1 more source

Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. [PDF]

open access: yesPLoS ONE, 2013
How cells integrate multiple patterning signals to achieve early endoderm regionalization remains largely unknown. Between gastrulation and neurulation, retinoic acid (RA) signaling is required, while Wnt/β-catenin signaling has to be repressed for the ...
Tiejun Zhang   +2 more
doaj   +1 more source

Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis [PDF]

open access: yes, 2011
Background The Sleeping Beauty (SB) transposon system has been used for germline transgenesis of the diploid frog, Xenopus tropicalis. Injecting one-cell embryos with plasmid DNA harboring an SB transposon substrate together with mRNA encoding the SB ...
Donald A Yergeau   +7 more
core   +2 more sources

BINge: Multispecies Ortholog Clustering for Differential Gene Expression Analyses

open access: yesMolecular Ecology Resources, Volume 26, Issue 4, May 2026.
ABSTRACT Differential gene expression (DGE) analysis enables researchers to investigate the link between gene expression and the phenotypic responses observed in organisms across time, experimental, or field conditions. Accurate quantification of gene expression is essential when performing DGE experiments, with a range of methods having been developed
Zachary Stewart   +3 more
wiley   +1 more source

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