Results 71 to 80 of about 58,345 (189)

Highly efficient bi-allelic mutation rates using TALENs in Xenopus tropicalis

Biology Open, 2012
Summary In the past decade, Xenopus tropicalis has emerged as a powerful new amphibian genetic model system, which offers all of the experimental advantages of its larger cousin, Xenopus laevis.
Shoko Ishibashi, Rebecca Cliffe, Enrique Amaya   +2 more
doaj   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, Volume 13, Issue 58, 19 October 2026.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Genome-wide identification of Xenopus matrix metalloproteinases: conservation and unique duplications in amphibians

BMC Genomics, 2009
Background Matrix metalloproteinases (MMPs) are members of the superfamily of Zn2+ dependent extracellular or membrane-bound endopeptidases which have been implicated to play critical roles in vertebrate development and human pathogenesis.
Mathew Smita, Das Biswajit, Fu Liezhen, Shi Yun-Bo   +3 more
doaj   +1 more source

Patterns of Proliferation in the Pacific Hagfish (Eptatretus stoutii) Retina Suggest an Ancient Origin for Adult Neurogenesis

Journal of Comparative Neurology, Volume 534, Issue 10, October 2026.
The hagfish, a jawless early‐branching vertebrate, has very rudimentary eyes that are diminutive and oddly devoid of melanin pigment. Yet, the degenerate hagfish eye grows throughout life and expresses canonical genes of vertebrate retinal development. ABSTRACT Comparative morphology has revealed fascinating structural and organizational differences in
Sarah N. Bradshaw, William T. Allison
wiley   +1 more source

Identification of Variants in Two Families With Congenital Cataract by Whole Exome Sequencing

Molecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
We describe likely pathogenic missense variants causing congenital cataract and investigate these variants using high‐throughput gene sequencing, Sanger sequencing, bioinformatics, and computational biology tools. Our findings provide novel insights into the molecular diagnosis of congenital cataract and have important implications for genetic ...
Yazhou Huang, Xinwei Leng, Jibo Zhang, Xingxin Fang, Ting He, Lihua Zhou, Zhenkai Wu, Yuankun Wang, Dan Peng   +8 more
wiley   +1 more source

Genomic Signatures of Endemic Pathogen Exposure in a Declining Amphibian

Molecular Ecology, Volume 35, Issue 20, October 2026.
ABSTRACT Endemic wildlife diseases can impose strong selection on threatened populations, yet whether persistence is associated with adaptive genomic responses remains poorly understood. We tested whether long‐term exposure to Batrachochytrium dendrobatidis (Bd) following population declines has left detectable selection signatures in the genome of the
Alexander S. Wendt, Lee Berger, Lee F. Skerratt, Laura A. Brannelly   +3 more
wiley   +1 more source

A New Nomenclature of Xenopus laevis Chromosomes Based on the Phylogenetic Relationship to Silurana/Xenopus tropicalis

, 2015
Xenopus laevis (XLA) is an allotetraploid species which appears to have undergone whole-genome duplication after the interspecific hybridization of 2 diploid species closely related to Silurana/Xenopus tropicalis (XTR). Previous cDNA fluorescence in situ
Gilchrist, Michael J., Zorn, Aaron M., Matsuda, Yoichi, Rokhsar, Daniel S., Uno, Yoshinobu, Taira, Masanori, Schmid, Michael, Kondo, Mariko   +7 more
core   +1 more source

Transcription and Three‐Dimensional Genome Organization: Cause, Consequence, or Coordination?

BioEssays, Volume 48, Issue 9, September 2026.
Transcription and 3D genome organization influence each other across spatial scales. Large‐scale architecture provides a relatively stable framework, while transcription and shared architectural factors refine local chromatin loops and domain boundaries. Specific long‐range interactions between regulatory elements and distal anchors can override domain‐
Dagyeong Yang, Elissa P. Lei
wiley   +1 more source

Overlapping effects on gene expression in response to Cic knockdown in Xenopus tropicalis and ectodermal wounding in Xenopus laevis.

, 2023
Xenopus laevis wounding datasets from [50] were filtered to only include genes annotated in the Xenopus tropicalis genome (12992 genes). Datasets for 30–90 minutes post-wounding were combined and filtered according to the following criteria, fold up ...
Mary Elizabeth Pownall (17240991), Matthew Broadsmith (17240988), Helena West (17240985), Harry V. Isaacs (17240994), Laura M. Cowell (6279995), Paul Genever (4016666), Michael King (42679)   +6 more
core   +1 more source

Biocompatibility Assessment of Lithium‐Ion Battery Materials in Medical Devices

Small Structures, Volume 7, Issue 9, September 2026.
How safe are lithium‐ion battery materials for medical devices? Antimicrobial performance, cytotoxicity, and biotoxicity are systematically evaluated, and a multidimensional risk‐assessment framework is developed to classify materials from negligible to high risk.
Tingyu Hua, Ming Xu, Zhuofei Jia, Zhiwei Tao, He Yin, Jinzhi Lv, Shanshan Li, Jianan Wang, Wei Yan, Jinhai Wang, Yunlong Zhao   +10 more
wiley   +1 more source