Results 81 to 90 of about 15,671 (201)

Structural and functional divergence of growth hormone-releasing hormone receptors in early sarcopterygians: lungfish and Xenopus [PDF]

, 2013
The evolutionary trajectories of growth hormone-releasing hormone (GHRH) receptor remain enigmatic since the discovery of physiologically functional GHRH-GHRH receptor (GHRHR) in non-mammalian vertebrates in 2007.
Chow, BKC, Lee, TO, TAM, KV
core   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, Volume 293, Issue 8, Page 2248-2269, April 2026.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Thyroid hormone receptor subtype-specific function in controlling organ-specific developmental timing and rate during Xenopus development

Frontiers in Endocrinology
Thyroid hormone (T3) is essential for vertebrate development as animals fail to develop into adults in the absence of T3. T3 is particularly critical for postembryonic development.
Yuta Tanizaki, Yun-Bo Shi
doaj   +1 more source

Highly efficient bi-allelic mutation rates using TALENs in Xenopus tropicalis

Biology Open, 2012
Summary In the past decade, Xenopus tropicalis has emerged as a powerful new amphibian genetic model system, which offers all of the experimental advantages of its larger cousin, Xenopus laevis.
Shoko Ishibashi, Rebecca Cliffe, Enrique Amaya   +2 more
doaj   +1 more source

Cartilage on the Move: Cartilage Lineage Tracing During Tadpole Metamorphosis

, 2012
The reorganization of cranial cartilages during tadpole metamorphosis is a set of complex processes. The fates of larval cartilage-forming cells (chondrocytes) and sources of adult chondrocytes are largely unknown.
Brittain, Alison L., Buchholz, Daniel R., Hall, Brian K., Kerney, Ryan R.   +3 more
core   +1 more source

Characterization of NLRP3 isoforms in bullfrog Aquarana catesbeiana and their role in antibacterial immunity

Journal of the World Aquaculture Society, Volume 57, Issue 2, April 2026.
Abstract The NLRP3 inflammasome is essential for innate immunity against pathogens, yet its function in amphibians remains poorly understood. Here, we identified and cloned two novel isoforms of NLRP3 from the American bullfrog (Aquarana catesbeiana), designated AcNLRP3 X1 and AcNLRP3 X2, with open reading frames of 2397 bp (798 aa) and 2874 bp (957 aa)
Peikui Yang, Jiayi Chen, Yixian Lin, Boxi Zeng, Tongying Chen, Jude Juventus Aweya, Xianghui Zou, Yuzhong Zheng, Ruixuan Wang   +8 more
wiley   +1 more source

Genome-wide identification of Xenopus matrix metalloproteinases: conservation and unique duplications in amphibians

BMC Genomics, 2009
Background Matrix metalloproteinases (MMPs) are members of the superfamily of Zn2+ dependent extracellular or membrane-bound endopeptidases which have been implicated to play critical roles in vertebrate development and human pathogenesis.
Mathew Smita, Das Biswajit, Fu Liezhen, Shi Yun-Bo   +3 more
doaj   +1 more source

The genomic environment around the Aromatase gene: evolutionary insights [PDF]

, 2005
Background The cytochrome P450 aromatase (CYP19), catalyses the aromatisation of androgens to estrogens, a key mechanism in vertebrate reproductive physiology. A current evolutionary hypothesis suggests that CYP19 gene arose at the origin of vertebrates,
Reis-Henriques Maria A, Santos Miguel M, Castro L Filipe C   +2 more
core   +2 more sources

Identification of mutants in inbred Xenopus tropicalis

Mechanisms of Development, 2005
Xenopus tropicalis offers the potential for genetic analysis in an amphibian. In order to take advantage of this potential, we have been inbreeding strains of frogs for future mutagenesis. While inbreeding a population of Nigerian frogs, we identified three mutations in the genetic background of this strain.
Grammer, Timothy C., Khokha, Mustafa K., Lane, Maura A., Lam, Kentson, Harland, Richard M.   +4 more
openaire   +2 more sources

Genome‐wide identification and solute selectivity of aquaporins in the sharpnose sevengill shark, Heptranchias perlo

Physiological Reports, Volume 14, Issue 8, April 2026.
Abstract The aquaporin genes (aqps) are widely distributed among vertebrates. In cartilaginous fish, aqp3 and aqp10 are duplicated, whereas many species have lost aqp8. While the solute permeability of aquaglyceroporins and Aqp8 exhibits significant diversity, systematic evaluations of their activity within species are limited.
Shinichiro Hidaka, Ayumi Nagashima, Akira Kato   +2 more
wiley   +1 more source