Results 101 to 110 of about 58,345 (189)

Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration [PDF]

, 2011
Background: The molecular mechanisms governing vertebrate appendage regeneration remain poorly understood. Uncovering these mechanisms may lead to novel therapies aimed at alleviating human disfigurement and visible loss of function following injury ...
Bonev, Boyan, Gilchrist, Michael J., Lea, Robert, Timothy J Mohun, Love, Nick R., Nick R Love, Amaya, Enrique; id_orcid, Zeef, Leo Ah, Roberto Paredes, Enrique Amaya, Mohun, Timothy J., Chen, Yaoyao, Leo AH Zeef, Yaoyao Chen, Fairclough, Lynne, Paredes, Roberto, Boyan Bonev, Michael J Gilchrist, Lynne Fairclough, Robert Lea   +19 more
core   +1 more source

Xenopus Resources: Transgenic, Inbred and Mutant Animals, Training Opportunities, and Web-Based Support

Frontiers in Physiology, 2019
Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology.
Marko Horb, Marcin Wlizla, Anita Abu-Daya, Sean McNamara, Dominika Gajdasik, Takeshi Igawa, Atsushi Suzuki, Hajime Ogino, Anna Noble, Centre de Ressource Biologique Xenope team in France, Jacques Robert, Christina James-Zorn, Matthew Guille, Matthew Guille, Morgane Nicolas, Thomas Lafond, Daniel Boujard, Yann Audic, Brigitte Guillet   +18 more
doaj   +1 more source

CRISPR/Cas9-mediated knockout of Rb1 in Xenopus tropicalis

, 2018
At this time, no molecular targeted therapies exist for treatment of retinoblastoma. This can be, in part, attributed to the lack of animal models that allow for both rapid identification of novel therapeutic targets and hypothesis driven drug testing ...
Naert, Thomas, Vleminckx, Kris, Thomas Naert, Kris Vleminckx   +3 more
core   +1 more source

TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models

, 2017
The targeted nuclease revolution (TALENs, CRISPR/Cas9) now allows Xenopus researchers to rapidly generate custom on-demand genetic knockout models. These novel methods to perform reverse genetics are unprecedented and are fueling a wide array of human ...
Naert, Thomas, Vleminckx, Kris, Van Nieuwenhuysen, Tom   +2 more
core   +1 more source

Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs

Nature Communications
Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate cell and developmental model systems, notably the genus Xenopus.
Jessen V. Bredeson, Austin B. Mudd, Sofia Medina-Ruiz, Therese Mitros, Owen Kabnick Smith, Kelly E. Miller, Jessica B. Lyons, Sanjit S. Batra, Joseph Park, Kodiak C. Berkoff, Christopher Plott, Jane Grimwood, Jeremy Schmutz, Guadalupe Aguirre-Figueroa, Mustafa K. Khokha, Maura Lane, Isabelle Philipp, Mara Laslo, James Hanken, Gwenneg Kerdivel, Nicolas Buisine, Laurent M. Sachs, Daniel R. Buchholz, Taejoon Kwon, Heidi Smith-Parker, Marcos Gridi-Papp, Michael J. Ryan, Robert D. Denton, John H. Malone, John B. Wallingford, Aaron F. Straight, Rebecca Heald, Dirk Hockemeyer, Richard M. Harland, Daniel S. Rokhsar   +34 more
doaj   +1 more source

Fixation and Expansion Microscopy of Xenopus Egg Extract Spindles

Bio-Protocol
In vitro systems based on Xenopus egg extracts have elucidated many aspects of spindle assembly. Still, numerous unknowns remain, particularly concerning the variation in spindle morphologies. The X. laevis and X.
Gabriel Guilloux, Maiko Kitaoka, Karel Mocaer, Claire Heichette, Laurence Duchesne, Rebecca Heald, Thierry Pecot, Romain Gibeaux   +7 more
doaj   +1 more source

Sequencing and Analysis of 10967 Full-Length cDNA Clones from Xenopus Laevis and Xenopus Tropicalis [PDF]

, 2005
Sequencing of full-insert clones from full-length cDNA libraries from both Xenopus laevis and Xenopus tropicalis has been ongoing as part of the Xenopus Gene Collection initiative. Here we present an analysis of 10967 clones (8049 from X. laevis and 2918
Wong, D., Petrescu, A., Marra, M., Gerhard, D., Wagner, L., Chand, S., Green, E. D., Tsai, M., Brown-John, M., Myers, R. M., Barber, S., Butterfield, Y., Stott, J., Beland, J., Olson, T., Holt, R., Jones, S. M., Babakaiff, R., Matsuo, C., Mayo, M., Morin, R. D., Liao, N., Kirkpatrick, R., Smailus, D., Siddiqui, A., Chang, E., Yang, G., Klein, S., Griffith, M., Jang, W., Featherstone, R., Gibson, S., Lee, E., Prange, C.   +33 more
core  

Mycobacterium gordonae infection in a colony of African clawed frogs (Xenopus tropicalis)

, 2009
Mycobacterium gordonae is an occasional human pathogen associated with cutaneous infections and nodular granulomatous skin lesions. A case of cutaneous nodular infection caused by M.
Gallagher, Alec, Alec Gallagher, Sanchez-Morgado, Jose M., Johnson, Linda K., Linda K Johnson, José M Sánchez-Morgado   +5 more
core   +1 more source

Xenopus tropicalis

Xenopus tropicalis (Gray, 1864)COLLECTION MATERIAL. — Burkina Faso • 7 ♀ (SVL 34.5-55 mm), 9 subadults (SVL 23.2-32.9 mm); Houet province, Bobo-Dioulasso; 11.14979°N, – 4.22272°W; 280 m a.s.l.; II.1983; NA leg.; ZFMK 38659-65, 38688-96.FIELD MATERIAL.
Ayoro, Halamoussa Joëlle, Segniagbeto, Gabriel Hoinsoudé, Hema, Emmanuel Midibahaye, Penner, Johannes, Oueda, Adama, Dubois, Alain, Rödel, Mark-Oliver, Kabré, Gustave Boureima, Ohler, Annemarie   +8 more
openaire   +1 more source

Cloning and expression of the Cdx family from the frog Xenopus tropicalis

The caudal-related (Cdx) homeodomain transcription factors have a conserved role in the development of posterior structures in both vertebrates and invertebrates.
Keenan ID; Reece-Hoyes JS; Isaacs HV
core   +2 more sources