Results 91 to 100 of about 15,789 (195)

Genome-wide identification of Xenopus matrix metalloproteinases: conservation and unique duplications in amphibians

open access: yesBMC Genomics, 2009
Background Matrix metalloproteinases (MMPs) are members of the superfamily of Zn2+ dependent extracellular or membrane-bound endopeptidases which have been implicated to play critical roles in vertebrate development and human pathogenesis.
Mathew Smita   +3 more
doaj   +1 more source

The Genome of the Western Clawed Frog Xenopus tropicalis [PDF]

open access: yesScience, 2010
Frog Genome The African clawed frog Xenopus tropicalis is the first amphibian to have its genome sequenced. Hellsten et al. (p. 633
Hellsten, Uffe   +47 more
openaire   +3 more sources

Genome‐Wide Characterization of Sex‐Linked Regions in the Sangzhi Horned Toad (Boulenophrys sangzhiensis) Reveals Complex Sex Determination Mechanisms

open access: yesMolecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Sex chromosomes in amphibians exhibit substantial variability and often remain largely homomorphic, providing a powerful system for studying sex determination. The Sangzhi horned toad (Boulenophrys sangzhiensis) is an ideal model, but limited genomic resources have hindered insights into sex determination mechanisms.
Chun H. Huang   +8 more
wiley   +1 more source

The evolution, distribution and diversity of endogenous circoviral elements in vertebrate genomes [PDF]

open access: yes, 2018
Circoviruses (family Circoviridae) are small, non-enveloped viruses that have short, single-stranded DNA genomes. Circovirus sequences are frequently recovered in metagenomic investigations, indicating that these viruses are widespread, yet they remain ...
Dennis, Tristan P.W.   +5 more
core   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

open access: yesThe FEBS Journal, Volume 293, Issue 8, Page 2248-2269, April 2026.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola   +11 more
wiley   +1 more source

Genome-wide analysis of canonical Wnt target gene regulation in Xenopus tropicalis challenges β-catenin paradigm [PDF]

open access: yes, 2017
We would like to thank Ken Cho, Ira Blitz, Kris Vleminckx and Aaron Zorn for discussion and Adam Lynch for comments on the manuscript. The research of the authors is supported by the UK Biotechnology and Biological Sciences Research Council (BB/M001695/1)
Hoppler, Stefan, Nakamura, Yukio
core   +1 more source

Characterization of NLRP3 isoforms in bullfrog Aquarana catesbeiana and their role in antibacterial immunity

open access: yesJournal of the World Aquaculture Society, Volume 57, Issue 2, April 2026.
Abstract The NLRP3 inflammasome is essential for innate immunity against pathogens, yet its function in amphibians remains poorly understood. Here, we identified and cloned two novel isoforms of NLRP3 from the American bullfrog (Aquarana catesbeiana), designated AcNLRP3 X1 and AcNLRP3 X2, with open reading frames of 2397 bp (798 aa) and 2874 bp (957 aa)
Peikui Yang   +8 more
wiley   +1 more source

Techniques and probes for the study of Xenopus tropicalis development [PDF]

open access: yesDevelopmental Dynamics, 2002
AbstractThe frog Xenopus laevis has provided significant insights into developmental and cellular processes. However, X. laevis has an allotetraploid genome precluding its use in forward genetic analysis. Genetic analysis may be applicable to Xenopus (Silurana) tropicalis, which has a diploid genome and a shorter generation time.
Khokha, Mustafa K.   +14 more
openaire   +2 more sources

Frog origins: inferences based on ancestral reconstructions of locomotor performance and anatomy [PDF]

open access: yes, 2016
Frogs are the most species-rich and ecologically diverse group of amphibians and are characterized by a unique body plan including long legs, elongated ilia, and fused caudal vertebrae.
Boistel, Renaud   +8 more
core   +3 more sources

Genome‐wide identification and solute selectivity of aquaporins in the sharpnose sevengill shark, Heptranchias perlo

open access: yesPhysiological Reports, Volume 14, Issue 8, April 2026.
Abstract The aquaporin genes (aqps) are widely distributed among vertebrates. In cartilaginous fish, aqp3 and aqp10 are duplicated, whereas many species have lost aqp8. While the solute permeability of aquaglyceroporins and Aqp8 exhibits significant diversity, systematic evaluations of their activity within species are limited.
Shinichiro Hidaka   +2 more
wiley   +1 more source

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